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肾盂和输尿管肿瘤患者的生存率:一项回顾性研究。

Survival of patients with tumors of the renal pelvis and ureter: a retrospective study.

作者信息

Shimazui T, Uchida K, Kondo F, Takeshima H, Ishikawa H, Kano S, Koiso K

出版信息

Jpn J Clin Oncol. 1985 Dec;15(4):603-9.

PMID:4094093
Abstract

A review of 27 patients with renal pelvic tumors and ureteral tumors admitted to the Tsukuba University Hospital was performed retrospectively. Nineteen cases of renal pelvic tumors and eleven cases of ureteral tumors were submitted to the study. These patients were treated mainly by surgery. The rates for 1-year, 3-year, 5-year and 10-year survival were 88.5%, 57.6%, 40.3% and 20.2%, respectively. No obvious relationship between prognosis of renal pelvic tumor and that of ureteral tumors was seen. Pathologically, there was a correlation between the grade and the stage of the tumor. Prognosis was related to the stage of the tumor, but not to the grade of the tumor. Clinically, the patients with positive urinary cytology had a poorer prognosis. It was considered that no relationship existed between the preoperative clinical stage and the postoperative pathological stage. Consequently, the former is not considered a prognostic factor. We have been performing mainly radical nephroureterectomy with regional lymphadenectomy since 1975. The patients who received the operation with regional lymphadenectomy since 1975. The patients who received the operation with regional lymphadenectomy or with adjuvant chemotherapy had a better prognosis. It is concluded that lymphadenectomy is a valuable operation for improving prognosis.

摘要

我们对筑波大学医院收治的27例肾盂肿瘤和输尿管肿瘤患者进行了回顾性研究。其中肾盂肿瘤19例,输尿管肿瘤11例纳入本研究。这些患者主要接受手术治疗。1年、3年、5年和10年生存率分别为88.5%、57.6%、40.3%和20.2%。未发现肾盂肿瘤和输尿管肿瘤预后之间存在明显关联。病理上,肿瘤分级与分期之间存在相关性。预后与肿瘤分期有关,而与肿瘤分级无关。临床上,尿细胞学检查阳性的患者预后较差。术前临床分期与术后病理分期之间不存在相关性。因此,前者不被视为预后因素。自1975年以来,我们主要进行根治性肾输尿管切除术并区域淋巴结清扫。1975年以来接受区域淋巴结清扫手术的患者,以及接受区域淋巴结清扫或辅助化疗的患者预后较好。结论是淋巴结清扫术是改善预后的一项有价值的手术。

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