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Diagnostics (Basel). 2025 Aug 26;15(17):2151. doi: 10.3390/diagnostics15172151.
2
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本文引用的文献

1
A nomogram model based on the systemic immune-inflammation index to predict the risk of venous thromboembolism in elderly patients after hip fracture: A retrospective cohort study.基于全身免疫炎症指数的列线图模型预测老年髋部骨折患者静脉血栓栓塞风险：一项回顾性队列研究。
Heliyon. 2024 Mar 20;10(6):e28389. doi: 10.1016/j.heliyon.2024.e28389. eCollection 2024 Mar 30.
2
Prognostic Nutritional Index, Controlling Nutritional Status (CONUT) Score, and Inflammatory Biomarkers as Predictors of Deep Vein Thrombosis, Acute Pulmonary Embolism, and Mortality in COVID-19 Patients.预后营养指数、控制营养状况（CONUT）评分及炎症生物标志物作为COVID-19患者深静脉血栓形成、急性肺栓塞和死亡率的预测指标
Diagnostics (Basel). 2022 Nov 11;12(11):2757. doi: 10.3390/diagnostics12112757.
3
High level of neutrophil to lymphocyte ratio increases the risk of deep venous thrombosis in intensive care unit patients after oral cancer surgery: a retrospective study.中性粒细胞与淋巴细胞比值升高增加口腔癌术后重症监护病房患者深静脉血栓形成风险：一项回顾性研究
Ann Transl Med. 2022 Jul;10(14):763. doi: 10.21037/atm-22-2453.
4
Diagnostic and Prognostic Value of Immune/Inflammation Biomarkers for Venous Thromboembolism: Is It Reliable for Clinical Practice?免疫/炎症生物标志物对静脉血栓栓塞症的诊断和预后价值：对临床实践是否可靠？
J Inflamm Res. 2021 Oct 2;14:5059-5077. doi: 10.2147/JIR.S327014. eCollection 2021.
5
Relationship between the inflammation/immune indexes and deep venous thrombosis (DVT) incidence rate following tibial plateau fractures.炎症/免疫指标与胫骨平台骨折后深静脉血栓（DVT）发生率的关系。
J Orthop Surg Res. 2020 Jul 2;15(1):241. doi: 10.1186/s13018-020-01765-9.
6
How to control confounding effects by statistical analysis.如何通过统计分析控制混杂效应。
Gastroenterol Hepatol Bed Bench. 2012 Spring;5(2):79-83.

对穆雷桑等人的评论：预后营养指数、控制营养状况（CONUT）评分及炎症生物标志物作为COVID-19患者深静脉血栓形成、急性肺栓塞和死亡率的预测指标。2022年，，2757。

Comment on Mureșan et al. Prognostic Nutritional Index, Controlling Nutritional Status (CONUT) Score, and Inflammatory Biomarkers as Predictors of Deep Vein Thrombosis, Acute Pulmonary Embolism, and Mortality in COVID-19 Patients. 2022, , 2757.

作者信息

Lian Mengyi, Zhang Chengwei

机构信息

Department of Obstetrics and Gynecology, Longquan People's Hospital, Lishui 323700, China.

Innovative Regenerative Medicine, Graduate School of Medicine, Kansai Medical University, Osaka 573-1191, Japan.

出版信息

Diagnostics (Basel). 2025 Aug 26;15(17):2151. doi: 10.3390/diagnostics15172151.

DOI:10.3390/diagnostics15172151
PMID:40941640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12427815/
Abstract

We read with interest the study by Mureșan et al. on nutritional and inflammatory biomarkers predicting thromboembolic events and mortality in COVID-19 patients. The simultaneous independent significance of eight correlated biomarkers raises concerns about possible multicollinearity. We welcome the authors' clarification and updated multivariate results, which confirmed that several markers lost significance after adjustment. We recommend clearer statistical terminology and parallel reporting of univariate and multivariate results to improve transparency.

摘要

我们饶有兴趣地阅读了穆雷桑等人关于预测COVID-19患者血栓栓塞事件和死亡率的营养和炎症生物标志物的研究。八个相关生物标志物同时具有独立意义，这引发了对可能存在多重共线性的担忧。我们欢迎作者作出的澄清以及更新后的多变量结果，这些结果证实了一些标志物在调整后失去了显著性。我们建议使用更清晰的统计术语，并并行报告单变量和多变量结果，以提高透明度。