对穆雷桑等人的评论：预后营养指数、控制营养状况（CONUT）评分及炎症生物标志物作为COVID-19患者深静脉血栓形成、急性肺栓塞和死亡率的预测指标。2022年，，2757。
Comment on Mureșan et al. Prognostic Nutritional Index, Controlling Nutritional Status (CONUT) Score, and Inflammatory Biomarkers as Predictors of Deep Vein Thrombosis, Acute Pulmonary Embolism, and Mortality in COVID-19 Patients. 2022, , 2757.
作者信息
Lian Mengyi, Zhang Chengwei
机构信息
Department of Obstetrics and Gynecology, Longquan People's Hospital, Lishui 323700, China.
Innovative Regenerative Medicine, Graduate School of Medicine, Kansai Medical University, Osaka 573-1191, Japan.
出版信息
Diagnostics (Basel). 2025 Aug 26;15(17):2151. doi: 10.3390/diagnostics15172151.
Abstract
We read with interest the study by Mureșan et al. on nutritional and inflammatory biomarkers predicting thromboembolic events and mortality in COVID-19 patients. The simultaneous independent significance of eight correlated biomarkers raises concerns about possible multicollinearity. We welcome the authors' clarification and updated multivariate results, which confirmed that several markers lost significance after adjustment. We recommend clearer statistical terminology and parallel reporting of univariate and multivariate results to improve transparency.
摘要
我们饶有兴趣地阅读了穆雷桑等人关于预测COVID-19患者血栓栓塞事件和死亡率的营养和炎症生物标志物的研究。八个相关生物标志物同时具有独立意义，这引发了对可能存在多重共线性的担忧。我们欢迎作者作出的澄清以及更新后的多变量结果，这些结果证实了一些标志物在调整后失去了显著性。我们建议使用更清晰的统计术语，并并行报告单变量和多变量结果，以提高透明度。
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Comment on Mureșan et al. Prognostic Nutritional Index, Controlling Nutritional Status (CONUT) Score, and Inflammatory Biomarkers as Predictors of Deep Vein Thrombosis, Acute Pulmonary Embolism, and Mortality in COVID-19 Patients. 2022, , 2757.对穆雷桑等人的评论：预后营养指数、控制营养状况（CONUT）评分及炎症生物标志物作为COVID-19患者深静脉血栓形成、急性肺栓塞和死亡率的预测指标。2022年，，2757。
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