van Doan Cong, Bonzano Sara, Maffei Massimo E
Department of Life Sciences and Systems Biology, University of Turin, Via Quarello15/a, 10135 Turin, Italy.
Int J Mol Sci. 2025 Aug 30;26(17):8462. doi: 10.3390/ijms26178462.
The widespread use of rare earth elements (REEs) in agriculture, particularly Lanthanum (La), raises concerns about their ecological impact on non-target organisms. We investigated the direct and indirect effects of La on the insect pest and its host plant, . Direct exposure to La-supplemented diets reduced larval growth, survival, and egg production. Interestingly, a transgenerational effect was observed, where larvae from La-exposed parents exhibited increased resilience, showing no performance reduction on the same diets. Indirectly, La accumulation in plants mediated a hormetic response in herbivores, increasing larval weight at low concentrations but reducing it at high concentrations, while modulating their oxidative stress and detoxification gene expression. From the plant perspective, La exposure amplified herbivory-induced calcium signalling and altered the expression of key genes related to calcium and reactive oxygen species pathways. These findings reveal the complex ecological risks of La accumulation in agroecosystems, affecting both plants and insects directly and through novel transgenerational effects.
稀土元素（REEs）在农业中的广泛应用，尤其是镧（La），引发了人们对其对非目标生物生态影响的担忧。我们研究了镧对害虫及其寄主植物的直接和间接影响。直接接触添加镧的食物会降低幼虫的生长、存活率和产卵量。有趣的是，观察到了一种跨代效应，即来自接触过镧的亲本的幼虫表现出更强的恢复力，在相同食物条件下其性能没有下降。间接而言，植物中镧的积累介导了食草动物的兴奋效应，低浓度时增加幼虫体重，高浓度时则降低，同时调节其氧化应激和解毒基因表达。从植物角度来看，镧暴露增强了食草动物诱导的钙信号传导，并改变了与钙和活性氧途径相关的关键基因的表达。这些发现揭示了农业生态系统中镧积累的复杂生态风险，直接以及通过新的跨代效应影响植物和昆虫。
