Masarone Daniele, Gravino Rita, Falco Luigi, Catapano Dario, Valente Fabio, Amarelli Cristiano, Marra Claudio, Kittleson Michelle, Silverio Pierino Di, Lorenzo Emilio di
Department of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Department of Cardiac Surgery and Transplant, AORN dei Colli-Monaldi Hospital, 80100 Naples, Italy.
J Clin Med. 2025 Sep 5;14(17):6290. doi: 10.3390/jcm14176290.
Scientists, physicians, and engineers have long endeavored to develop a device capable of replacing the function of the heart. The objective is to create a machine or pump for patients suffering from advanced biventricular heart failure, where survival until transplantation is feasible. These total artificial hearts are designed to sustain the patient until a donor heart becomes available. This review aims to present an overview and historical context of the development of the total artificial heart, analyze the currently utilized devices, and briefly discuss future technological innovations in total artificial heart systems.
长期以来,科学家、医生和工程师一直致力于研发一种能够替代心脏功能的装置。目标是为患有晚期双心室心力衰竭且有望存活至接受心脏移植的患者制造一台机器或泵。这些全人工心脏旨在维持患者生命,直至有供体心脏可用。本综述旨在概述全人工心脏的发展历程并介绍其历史背景,分析当前使用的装置,并简要讨论全人工心脏系统未来的技术创新。