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最佳编织型血管内桥接(WEB)装置与动脉瘤体积:使用自动容积软件预测WEB治疗后动脉瘤的闭塞状态

Optimal woven endobridge (WEB) device-aneurysm volume: using automated volumetric software to predict aneurysmal occlusion status after WEB treatment.

作者信息

Kawamura Yosuke, Takigawa Tomoji, Nagaishi Masaya, Hyodo Akio, Suzuki Kensuke

机构信息

Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami Koshigaya, Koshigaya Shi, Saitama, 343-8555, Japan.

Department of Neuroendovascular, Kamagaya General Hospital, Chiba, Japan.

出版信息

Acta Neurochir (Wien). 2025 Sep 13;167(1):246. doi: 10.1007/s00701-025-06558-9.

Abstract

BACKGROUND

Optimal Woven EndoBridge (WEB) sizing is crucial for successful implantation. We used three-dimensional (3D) software, Siemens Aneurysm Analysis v. VD30B, to determine the potential of WEB device-aneurysm volume (DAV) ratios in predicting post-treatment occlusion status.

METHODS

We retrospectively reviewed 35 unruptured intracranial wide-neck bifurcation aneurysms treated using the WEB. The study evaluated the association between the DAV ratio and aneurysm obliteration during follow-up. The primary aim of the study was to determine the optimal DAV ratio for predicting occlusion status following WEB treatment.

RESULTS

The success rate of treating all unruptured aneurysms with the WEB was 100%. The median duration to final follow-up was 365 ± 184.0 days with all 35 patients having a mean modified Rankin Scale score of 0. One (2.9%) patient experienced a transient ischemic attack with hemiparesis perioperatively. A follow-up angiography revealed complete occlusion (WEB Occlusion Scale [WOS] A and B) in 25 (71.4%) of 35 patients and WOS C and D in 10 (28.6%) of 35. The median DAV ratio significantly differed between the groups. The median DAV ratios were 0.97 in the complete occlusion group and 0.84 in the WOS C and D group, respectively (p = 0.002). A receiver operating characteristic curve produced an area under the curve of 0.76 (confidence interval: 0.56-0.96). The optimal DAV ratio cut-off and the highest Youden index for complete occlusion was 0.90.

CONCLUSION

Calculating DAV ratios using 3D software may help improve the rate of complete occlusion following WEB treatment.

摘要

背景

最佳编织型血管内桥接装置(WEB)尺寸对于成功植入至关重要。我们使用三维(3D)软件西门子动脉瘤分析v. VD30B来确定WEB装置与动脉瘤体积比(DAV)在预测治疗后闭塞状态方面的潜力。

方法

我们回顾性分析了35例使用WEB治疗的未破裂颅内宽颈分叉动脉瘤。该研究评估了DAV比与随访期间动脉瘤闭塞之间的关联。该研究的主要目的是确定预测WEB治疗后闭塞状态的最佳DAV比。

结果

使用WEB治疗所有未破裂动脉瘤的成功率为100%。最终随访的中位持续时间为365±184.0天,所有35例患者的改良Rankin量表平均评分为0。1例(2.9%)患者在围手术期发生短暂性脑缺血发作并伴有偏瘫。随访血管造影显示,35例患者中有25例(71.4%)完全闭塞(WEB闭塞量表[WOS]A和B),35例中有10例(28.6%)为WOS C和D。两组之间的中位DAV比有显著差异。完全闭塞组的中位DAV比分别为0.97,WOS C和D组为0.84(p = 0.002)。受试者工作特征曲线下面积为0.76(置信区间:0.56 - 0.96)。完全闭塞的最佳DAV比临界值和最高约登指数为0.90。

结论

使用3D软件计算DAV比可能有助于提高WEB治疗后的完全闭塞率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19df/12433362/e8b81fa50d7a/701_2025_6558_Fig1_HTML.jpg

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