Gerdemann Lucas, Reith Wolfgang
Faculty of Medicine and University Hospital, Clinic for Diagnostic and Interventional Neuroradiology, Saarland University, Homburg, Germany.
Neuroradiology. 2025 Jun 11. doi: 10.1007/s00234-025-03673-3.
The Woven EndoBridge is a device for endovascular embolization of intracranial aneurysms. The aim of this study is to re-evaluate this treatment method regarding its safety and efficacy and to compare it with the results of alternative treatment strategies (clipping, coiling, etc.) and their outcome known from the literature.
Forty-four intracranial aneurysms treated with the Woven EndoBridge were retrospectively identified in a clinic for diagnostic and interventional neuroradiology. The average aneurysm height was 7.1 mm, and the average width was 5.8 mm. Further the average neck diameter (3.6 mm) and the average dome-to-neck ratio (1.6) were determined. Both ruptured and non-ruptured aneurysms were included in this study. Occlusion was assessed using the WEB Occlusion Scale immediately after the intervention and after three, six and twelve months follow-up.
In 11% of cases (n = 5), implantation of the Woven EndoBridge failed technically. In two patients, a thromboembolic event occurred during the intervention without consequential damage. During the observation period of twelve months, none of the study participants died because of the intervention. After twelve months, 95% of the treated aneurysms (n = 20) showed adequate occlusion.
Compared to other treatment strategies (clipping, coiling etc.) and their complication rates known from other studies, our results suggest that the Woven EndoBridge is a safe treatment option. Regarding the angiographic results, the Woven EndoBridge achieves occlusion rates which are comparable with those of intravascular flow diverters, but without the need of dual anti-platelet-aggregation therapy.
编织式血管内桥接器(Woven EndoBridge)是一种用于颅内动脉瘤血管内栓塞的装置。本研究的目的是重新评估这种治疗方法的安全性和有效性,并将其与其他治疗策略(夹闭、栓塞等)的结果以及文献中已知的这些策略的治疗效果进行比较。
在一家诊断和介入神经放射学诊所中,对44例使用编织式血管内桥接器治疗的颅内动脉瘤进行回顾性分析。动脉瘤平均高度为7.1毫米,平均宽度为5.8毫米。此外,还测定了平均瘤颈直径(3.6毫米)和平均瘤顶与瘤颈比值(1.6)。本研究纳入了破裂和未破裂的动脉瘤。干预后立即以及在随访3个月、6个月和12个月后,使用WEB闭塞量表评估闭塞情况。
在11%的病例(n = 5)中,编织式血管内桥接器的植入在技术上失败。在两名患者中,干预期间发生了血栓栓塞事件,但未造成后果性损害。在12个月的观察期内,没有研究参与者因干预死亡。12个月后,95%(n = 20)的治疗动脉瘤显示出充分闭塞。
与其他治疗策略(夹闭、栓塞等)及其在其他研究中已知的并发症发生率相比,我们的结果表明编织式血管内桥接器是一种安全的治疗选择。关于血管造影结果,编织式血管内桥接器实现的闭塞率与血管内血流导向装置相当,但无需双联抗血小板聚集治疗。