Bojuwoye J B, Pease P E, Allan R N
Microbios. 1985;43(174-175):149-56.
Forty-five strains of Y enterocolitica including eleven from ankylosing spondylitis patients were examined for their ability to invade Hep-2 cells in culture. Nineteen out of twenty pathogenic strains were invasive and the rest were non-invasive. Three pathogenic strains were invasive, and three non-pathogenic strains were not invasive to human foetal gut. Invasiveness was not found to be useful for differentiating ankylosing spondylitis from non-ankylosing spondylitis strains.
检测了45株小肠结肠炎耶尔森菌,其中11株来自强直性脊柱炎患者,观察它们在培养物中侵袭Hep - 2细胞的能力。20株致病菌株中有19株具有侵袭性,其余为非侵袭性。3株致病菌株具有侵袭性,3株非致病菌株对人胎儿肠道无侵袭性。未发现侵袭性有助于区分强直性脊柱炎菌株和非强直性脊柱炎菌株。