Ren Yanqiao, Chen Chao, Song Songlin, Liu Yiming, Liu Jiacheng, Zhou Guofeng, Liang Bin, Zheng Chuansheng
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Wuhan, China.
Cardiovasc Diagn Ther. 2025 Aug 30;15(4):792-801. doi: 10.21037/cdt-2024-694. Epub 2025 Aug 12.
Hemoptysis is a prevalent symptom among patients with respiratory diseases, and those experiencing hemoptysis from non-bronchial artery sources are particularly susceptible to recurrence following treatment. This study aimed to evaluate the therapeutic effect of angiogram computed tomography (Angio-CT) on bronchial artery embolization (BAE) in patients with non-bronchial systemic arteries (NBSA).
This retrospective study included a total of 100 patients experiencing hemoptysis due to various etiologies between January 2020 and June 2024 in Huazhong University of Science and Technology Tongji Medical College Affiliated Union Hospital. The patients were divided into two groups: BAE treatment combined with Angio-CT group (n=60); Conventional BAE treatment group (n=40). A total of 26 and 14 patients in each group experienced hemoptysis attributed to NBSA. Clinical data were recorded, including age, gender, volume of hemoptysis, etc. Hemoptysis-free survival and overall survival were illustrated using Kaplan-Meier curves. The log-rank test was used to assess the differences in hemoptysis-free survival and overall survival between the two groups.
Technical success was achieved in all patients. There were no statistical differences in clinical success rate (90.0% 91.7%, P=0.78). The difference in recurrence rates between the two patient groups is statistically significant (11.7% 27.5%, P=0.04). And among patients with NBSA, the Angio-CT group exhibited a higher recurrence rate without hemoptysis compared to the traditional BAE group (P=0.04). In contrast, there was no significant difference in recurrence rates between the two groups of patients without NBSA (P=0.68).
The application of Angio-CT in guiding the treatment of NBSA-related hemoptysis offers superior clinical outcomes compared to conventional approaches. These findings could provide valuable evidence for refining therapeutic strategies, ultimately improving patient management in hemoptysis cases.
咯血是呼吸系统疾病患者的常见症状，那些非支气管动脉来源咯血的患者在治疗后特别容易复发。本研究旨在评估血管造影计算机断层扫描（Angio-CT）对非支气管体动脉（NBSA）患者支气管动脉栓塞术（BAE）的治疗效果。
这项回顾性研究纳入了2020年1月至2024年6月在华中科技大学同济医学院附属协和医院因各种病因咯血的100例患者。患者分为两组：BAE治疗联合Angio-CT组（n=60）；传统BAE治疗组（n=40）。每组分别有26例和14例患者咯血归因于NBSA。记录临床资料，包括年龄、性别、咯血量等。采用Kaplan-Meier曲线描述无咯血生存期和总生存期。采用对数秩检验评估两组间无咯血生存期和总生存期的差异。
所有患者均取得技术成功。临床成功率无统计学差异（90.0%对91.7%，P=0.78）。两组患者复发率差异有统计学意义（11.7%对27.5%，P=0.04）。在NBSA患者中，Angio-CT组无咯血复发率高于传统BAE组（P=0.04）。相比之下，两组无NBSA患者的复发率无显著差异（P=0.68）。
与传统方法相比，Angio-CT在指导NBSA相关咯血治疗中的应用具有更好的临床效果。这些发现可为完善治疗策略提供有价值的证据，最终改善咯血患者的管理。
