Ronconi G F, Ronconi M, Pesenti P, Soffiati G, Sposetti R, Zanardo V
Pediatr Med Chir. 1985 Mar-Apr;7(2):225-8.
We have studied plasma levels of Anti Diuretic Hormone (ADH) and its relationship to mode of delivery in 21 mothers and in their newborns. On the basis of the mode of delivery, mothers were divided into three subgroups: vaginal delivery before administration of oxytocin; vaginal delivery after administration of oxytocin; caesarean section. The infants are divided into two subgroups: neonates born by vaginal delivery (14 cases); neonates born by caesarean section (7 cases). ADH levels were determined at birth and in third day of life in the neonates. ADH determination was made by Radioimmunoassay (RIA). A noticeable rise in hormone levels was found in infants born by vaginal delivery, but not in neonates born by caesarean section. In third day of life ADH levels were comparable in all neonates. No significant difference was encountered in ADH levels among the subgroups of mothers. There was no correlation between ADH levels and: maternal age, placental weight, duration of labor, period of gestation of the mothers; neonatal weight, gestational age, body weight in 3rd day of life of the neonates; plasma sodium and osmolality both of the mothers and of the neonates. High levels of ADH in neonates delivered vaginally may contribute to increase the blood flow to the placenta and to other vital structures of the fetus during labour.
我们研究了21位母亲及其新生儿体内抗利尿激素(ADH)的血浆水平及其与分娩方式的关系。根据分娩方式,母亲被分为三个亚组:催产素给药前经阴道分娩;催产素给药后经阴道分娩;剖宫产。婴儿被分为两个亚组:经阴道分娩的新生儿(14例);剖宫产出生的新生儿(7例)。在新生儿出生时和出生后第三天测定ADH水平。采用放射免疫分析法(RIA)测定ADH。发现经阴道分娩的婴儿体内激素水平显著升高,但剖宫产出生的新生儿则没有。在出生后第三天,所有新生儿的ADH水平相当。母亲亚组之间的ADH水平没有显著差异。ADH水平与以下因素之间没有相关性:母亲年龄、胎盘重量、产程、母亲的妊娠期;新生儿体重、胎龄、新生儿出生后第三天的体重;母亲和新生儿的血浆钠和渗透压。经阴道分娩的新生儿体内高水平的ADH可能有助于在分娩过程中增加胎盘和胎儿其他重要结构的血流量。