Shiwaku Hironari, Shiwaku Akio, Sato Seiya, Yamauchi Kosuke, Hasegawa Suguru
Department of Gastroenterological Surgery Fukuoka University Faculty of Medicine Fukuoka Japan.
DEN Open. 2025 Sep 10;6(1):e70195. doi: 10.1002/deo2.70195. eCollection 2026 Apr.
In endoscopic full-thickness resection (EFTR), luminal collapse can occur due to communication between the gastrointestinal lumen and peritoneal cavity, making visualization and procedural continuity difficult. We propose the underwater pressure lumen expansion (UPLE) method, in which hydraulic pressure is applied in a fluid-filled environment to re-expand the collapsed lumen, thereby restoring visualization and allowing continued endoscopic manipulation. The UPLE method was applied during peroral endoscopic tumor resection in a clinical case and in an animal model of EFTR, and its utility was successfully demonstrated.
在内镜全层切除术（EFTR）中，由于胃肠道腔与腹腔相通，可能会发生管腔塌陷，这使得可视化和操作的连续性变得困难。我们提出了水下压力管腔扩张（UPLE）方法，即在充满液体的环境中施加液压，使塌陷的管腔重新扩张，从而恢复可视化并允许继续进行内镜操作。UPLE方法已应用于1例临床病例的经口内镜肿瘤切除术以及EFTR动物模型中，并成功证明了其效用。
