Alsulaiman Omer A, Alsaati Ahmed A, Alsaif Nasser Mohammed, Al-Husain Khalid M, Al-Jindan Fatma A, Algamdi Bader N
Department of Dermatology, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
Internal Medicine Department, Jubail General Hospital, Jubail, Saudi Arabia.
Int Med Case Rep J. 2025 Sep 8;18:1167-1173. doi: 10.2147/IMCRJ.S546576. eCollection 2025.
A 22-year-old incarcerated Saudi man presented with a 2-day history of painful vesicles on the shaft of his circumcised penis that were unrelated to drug use, trauma, exposure to ill persons, or sexual intercourse. Initial laboratory tests were normal, and the patient was initially diagnosed with herpes simplex infection. Due to nonadherence to the initial antiviral treatment, the lesions progressed, leading to a revised diagnosis of chancroid. Subsequent testing ruled out sexually transmitted infections and revealed methicillin-resistant Staphylococcus aureus in the culture of the purulent exudate. Histopathology confirmed balanitis circumscripta plasmacellularis (BCP, zoon's balanitis). The lesion responded well to topical betamethasone, with marked clinical improvement over 2 months. This case highlights that although rare, BCP should be considered in circumcised patients with non-venereal genital lesions. Additionally, it underscores that early histopathological confirmation is essential to avoid misdiagnosis and inappropriate treatment.
一名22岁被监禁的沙特男子，其包皮环切后的阴茎体部出现疼痛性水疱，病程2天，与吸毒、外伤、接触病人或性交无关。初始实验室检查正常，该患者最初被诊断为单纯疱疹感染。由于未坚持初始抗病毒治疗，皮损进展，导致修正诊断为软下疳。后续检测排除了性传播感染，并在脓性分泌物培养中发现耐甲氧西林金黄色葡萄球菌。组织病理学证实为浆细胞性局限性龟头炎（BCP，动物性龟头炎）。皮损对外用倍他米松反应良好，2个月内临床有明显改善。该病例突出表明，虽然BCP罕见，但对于有非性病性生殖器皮损的包皮环切患者应考虑此病。此外，它强调早期组织病理学确诊对于避免误诊和不恰当治疗至关重要。
