Zewdu Simachew, Daniel Abel, Abebe Amene, Abraham Zinabu, Elias Hailu, Belete Adamu
Department of Nursing, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia.
Department of Clinical Medicine and Surgery-Section of Infectious Diseases, University of Naples "Federico II", Via Sergio Pansini, Naples Berhan, Italy.
Front Surg. 2025 Aug 28;12:1571033. doi: 10.3389/fsurg.2025.1571033. eCollection 2025.
Surgical site infections (SSIs) are a leading cause of morbidity and mortality worldwide. Particularly, in low- and middle-income countries (LMICs), they are the most prevalent kind of healthcare-associated infection (HAI), and they play a role in the emergence of antibiotic resistance, which can result in serious illnesses. Therefore, this study aims to ascertain the burden and association of surgical site infection among patients on the surgical ward in resource-limited surgical setups.
An institutional-based cross-sectional study was conducted in Wolaita Sodo University Comprehensive Specialized Hospital from March 1, 2022 to July 30, 2023. A systematic random sampling method was employed. Data management and statistical analysis were performed using SPSS version 25. An adjusted odds ratio (AOR) with 95% confidence interval was used to measure the association between dependent and independent variables. A -value < 0.05 was used to determine the level of significance.
This study included a total of 309 patients, of whom 198 (64.1%) were males. The average age of the participants was 42, and participants more than 42 years' old totaled 156 (50.5%); the type of residence was found to be rural for 236 patients (84.6%). The magnitude of surgical site infection was calculated to be 29.1%. Predisposing factors for surgical site infection included male sex (AOR -4.9; 95%; 2.0-11.3), drainage use (AOR -4.46; 95%; 1.9-10.3), and abdominal surgery (AOR-4.3; 95%; 1.3-14.1), whereas protective factors included younger female sex, elective surgery, and a surgery duration of less than 2 h.
手术部位感染(SSIs)是全球发病和死亡的主要原因。特别是在低收入和中等收入国家(LMICs),它们是最常见的医疗相关感染(HAI)类型,并且在抗生素耐药性的出现中起作用,这可能导致严重疾病。因此,本研究旨在确定资源有限的手术环境中外科病房患者手术部位感染的负担及相关性。
2022年3月1日至2023年7月30日在沃莱塔索多大学综合专科医院进行了一项基于机构的横断面研究。采用系统随机抽样方法。使用SPSS 25版进行数据管理和统计分析。使用95%置信区间的调整比值比(AOR)来衡量因变量和自变量之间的关联。P值<0.05用于确定显著性水平。
本研究共纳入309例患者,其中198例(64.1%)为男性。参与者的平均年龄为42岁,42岁以上的参与者共有156例(50.5%);发现236例患者(84.6%)的居住类型为农村。手术部位感染的发生率经计算为29.1%。手术部位感染的易感因素包括男性(AOR -4.9;95%;2.0 - 11.3)、使用引流(AOR -4.46;95%;1.9 - 10.3)和腹部手术(AOR -4.3;95%;1.3 - 14.1),而保护因素包括年轻女性、择期手术和手术持续时间少于2小时。