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成人Crowe II/III型发育性髋关节发育不良自体股骨头结构性植骨联合全髋关节置换术的临床疗效及预后分析

Clinical efficacy and prognostic analysis of autologous femoral head structural bone grafting combined with total hip arthroplasty for Crowe Type II/III developmental dysplasia of the hip in adults.

作者信息

Li Chengyu, Pei Fang, Wan Feng, Meng Baiyi

机构信息

Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University Xuzhou 221000, Jiangsu, China.

出版信息

Am J Transl Res. 2025 Aug 15;17(8):5987-5998. doi: 10.62347/TUYG1784. eCollection 2025.

Abstract

OBJECTIVE

To evaluate the clinical efficacy and mid-term outcomes of total hip arthroplasty (THA) assisted by acetabular reconstruction using autologous femoral head structural bone grafting in patients with Crowe type II/III developmental dysplasia of the hip (DDH).

METHODS

A retrospective analysis was conducted on 100 patients (100 hips) with Crowe type II/III DDH who underwent THA at the Affiliated Hospital of Xuzhou Medical University between January 2019 and December 2022. All patients received autologous femoral head structural bone grafting for acetabular reconstruction during the procedure. Perioperative parameters, visual analogue scale (VAS) scores, limb length discrepancy (LLD), range of motion (ROM), hip function [Harris hip score and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)], incidence of complications, quality of life [Generic Quality of Life Inventory-74 (GQOLI-74)], and radiographic outcomes were assessed.

RESULTS

The mean follow-up duration was 10.78 ± 1.65 months. Postoperatively, the VAS score significantly decreased from 6.52 ± 2.58 to 1.73 ± 0.72 (P < 0.001), and the LLD reduced from 2.88 ± 0.54 cm to 0.92 ± 0.39 cm (P < 0.001). The Harris hip score increased from 58.23 ± 6.14 to 92.45 ± 5.82 (P < 0.001), while the WOMAC score decreased from 72.54 ± 8.61 to 18.34 ± 5.09 (P < 0.001). All domains of the GQOLI-74 score showed significant improvements (P < 0.001). The overall complication rate was 1.0%, and radiographic assessments confirmed bone healing.

CONCLUSION

THA assisted by autologous femoral head structural bone grafting is a safe and effective approach for treating Crowe type II/III DDH. It significantly enhances hip function, restores biomechanics, improves the quality of life, and is associated with a low complication rate and favorable mid-term outcomes.

摘要

目的

评估在采用自体股骨头结构性骨移植进行髋臼重建辅助下的全髋关节置换术(THA)治疗Crowe II/III型发育性髋关节发育不良(DDH)患者中的临床疗效及中期结果。

方法

对2019年1月至2022年12月期间在徐州医科大学附属医院接受THA的100例(100髋)Crowe II/III型DDH患者进行回顾性分析。所有患者在手术过程中均接受自体股骨头结构性骨移植进行髋臼重建。评估围手术期参数、视觉模拟评分(VAS)、肢体长度差异(LLD)、活动范围(ROM)、髋关节功能[Harris髋关节评分和西安大略和麦克马斯特大学骨关节炎指数(WOMAC)]、并发症发生率、生活质量[通用生活质量量表-74(GQOLI-74)]以及影像学结果。

结果

平均随访时间为10.78±1.65个月。术后,VAS评分从6.52±2.58显著降至1.73±0.72(P<0.001),LLD从2.88±0.54 cm降至0.92±0.39 cm(P<0.001)。Harris髋关节评分从58.23±6.14升至92.45±5.82(P<0.001),而WOMAC评分从72.54±8.61降至18.34±5.09(P<0.001)。GQOLI-74评分的所有领域均显示出显著改善(P<0.001)。总体并发症发生率为1.0%,影像学评估证实骨愈合。

结论

自体股骨头结构性骨移植辅助下的THA是治疗Crowe II/III型DDH的一种安全有效的方法。它能显著提高髋关节功能,恢复生物力学,改善生活质量,且并发症发生率低,中期结果良好。

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