Rahal Amel, Bennafaa Toufik, Kherrab Hanane, Djennane Nassima, Azzouz Malha
Department of Endocrinology, Bologhine Hospital, Algiers, Algeria.
Department of Neurosurgery, Mohamed Lamine Debaghine Hospital, Algiers, Algeria.
Pan Afr Med J. 2025 Jun 25;51:57. doi: 10.11604/pamj.2025.51.57.47982. eCollection 2025.
We report the case of a functional gonadotropic adenoma (FGA) in a 32-year-old woman, initially revealed by ovarian hyperstimulation. Hormonal investigations strongly suggested an FGA; pelvic ultrasound revealed macrofollicular ovarian enlargement. Despite a clear clinical picture, diagnosis was delayed until the appearance of cranial tumor syndrome with ophthalmological impairment and pituitary dysfunction. The ophthalmological emergency necessitated urgent surgery, allowing both decompression of the optic pathways and a reduction in hyperestrogenism. Despite their rarity, it is essential to recognize FGA to avoid potentially fatal complications.
我们报告了一例32岁女性功能性促性腺激素腺瘤（FGA）病例，最初因卵巢过度刺激而被发现。激素检查强烈提示为FGA；盆腔超声显示卵巢大卵泡增大。尽管临床表现明确，但诊断延迟至出现伴有眼科损害和垂体功能障碍的颅部肿瘤综合征。眼科急症需要紧急手术，以实现视神经通路减压和降低高雌激素血症。尽管FGA罕见，但认识到它对于避免潜在的致命并发症至关重要。
