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病例报告:肝脏同时出现两个腺瘤样瘤。

Case Report: Concurrent two adenomatoid tumors of liver.

作者信息

Bi Lei

机构信息

Department of Radiology, Shandong Provincial Hospital, Jinan, China.

Department of Radiology, Linyi People's Hospital, Linyi, China.

出版信息

Front Oncol. 2025 Aug 28;15:1640018. doi: 10.3389/fonc.2025.1640018. eCollection 2025.

Abstract

A 40-year-old man with two accidentally discovered subcapsular liver tumors was admitted to our hospital for further treatment. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed two hypervascular lesions, which showed marked enhancement in arterial phase and prolonged enhancement in portal venous phase. The patient had not received any prior treatment, and the two lesions were pathologically confirmed after partial hepatectomy. Hematoxylin-eosin staining revealed a partially cystic, highly vascular, and well-encapsulated neoplasm. Immunohistochemistry findings demonstrated that the epithelioid tumor cells were positive for vimentin, calretinin, WT-1, cytokeratin, CD 31, CD 34, and D2-40, which supported their mesothelial origin. Immunohistochemistry for a mesothelial marker should be performed for determining the presence of an adenomatoid tumor when benign epithelioid cells are seen.

摘要

一名40岁男性因意外发现两个肝包膜下肿瘤而入院接受进一步治疗。计算机断层扫描(CT)和磁共振成像(MRI)显示两个高血运病变,动脉期明显强化,门静脉期强化持续。该患者此前未接受过任何治疗,部分肝切除术后这两个病变经病理证实。苏木精-伊红染色显示为部分囊性、高血运且包膜完整的肿瘤。免疫组化结果表明,上皮样肿瘤细胞波形蛋白、钙网膜蛋白、WT-1、细胞角蛋白、CD 31、CD 34和D2-40呈阳性,支持其间皮来源。当见到良性上皮样细胞时,应进行间皮标记物的免疫组化检查以确定是否存在腺瘤样肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a64/12422893/061c6f897753/fonc-15-1640018-g001.jpg

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