Ferrando R, Truhaut R, Gak J C, Graillot C, Fourlon C
C R Acad Hebd Seances Acad Sci D. 1977 Jun 20;284(23):2419-21.
A 5 P. 100 level of protein from casein in a diet does not allow vitamin A to modify significantly induction of cytochrome P 450 on the Rat receiving or not receiving DDT. When the protein increases to a 15 p. 100 level, the induction is better providing vitamin A is to be given. If protein and vitamin A are necessary for cytochrom P 450 induction, an increase of protein level remains inefficient without vitamin A.
饮食中酪蛋白含量为5%时,无论给大鼠喂食滴滴涕与否,维生素A都无法显著改变细胞色素P450的诱导情况。当蛋白质含量增至15%时,如果给予维生素A,诱导效果会更好。如果蛋白质和维生素A对细胞色素P450的诱导是必需的,那么在没有维生素A的情况下,提高蛋白质水平仍然无效。