Munthakheem Shaik Mohammed, Joshi Amol Kalyanrao, Deshmukh Laxmikant Sheshrao, Londhe Atul C
Department of Neonatology, Government Medical College, Aurangabad, Maharashtra, India.
Indian Pediatr. 2025 Sep 15. doi: 10.1007/s13312-025-00183-6.
To reduce the ventilator-associated pneumonia (VAP) rate by improving the compliance of components of the VAP prevention bundle to > 90% over a period of 35 weeks.
This quality improvement study was conducted in the neonatal intensive care unit (NICU) of a tertiary care public hospital from May 2023 to March 2025. Baseline VAP rate was determined, and a team of all the stakeholders was formed. The problem was analyzed using various tools, and the main contributing factors for poor compliance with VAP bundle care were identified with the corresponding solution framed using the mnemonic H-ER-O-S: hand hygiene/head-end elevation, education/extubation readiness, oral care, suction care. Multiple plan-do-study-act (PDSA) cycles were done using point-of-care quality improvement (POCQI) methodology. The data were collected prospectively and analyzed regularly with the team members, and actions were planned accordingly.
The VAP rate (per 1000 ventilator days) decreased significantly from 49.5 at baseline (May 2023) to 32.51 (95% CI 18.66-46.37) in the intervention phase and sustained at 6.40 (95% CI 4.58-8.93) for a consecutive 14 months (February 2024 till March 2025). The baseline compliance for components of VAP care bundle increased from 57.9% (95% CI 54.5-61.2) to 88.3% (95% CI 86.9-89.7) and was sustained for 14 months at 94.0% (95% CI 93.3-94.8, P < 0.001).
POCQI principles targeting the H-ER-O-S protocol help reduce VAP rates by increasing the compliance with the VAP care bundle.
在35周的时间内,通过将呼吸机相关性肺炎(VAP)预防集束护理各组成部分的依从性提高至90%以上,降低VAP发生率。
本质量改进研究于2023年5月至2025年3月在一家三级公立教学医院的新生儿重症监护病房(NICU)开展。测定基线VAP发生率,并组建了一个由所有利益相关者组成的团队。使用各种工具对问题进行分析,确定VAP集束护理依从性差的主要促成因素,并使用助记符H-ER-O-S制定相应解决方案:手卫生/床头抬高、教育/拔管准备、口腔护理、吸痰护理。采用即时质量改进(POCQI)方法进行多次计划-实施-研究-改进(PDSA)循环。前瞻性收集数据,并与团队成员定期进行分析,据此制定相应行动。
VAP发生率(每1000个呼吸机日)从基线时(2023年5月)的49.5显著降至干预阶段的32.51(95%CI 18.66-46.37),并在连续14个月(2024年2月至2025年3月)维持在6.40(95%CI 4.58-8.93)。VAP护理集束各组成部分的基线依从性从57.9%(95%CI 54.5-61.2)提高至88.3%(95%CI 86.9-89.7),并在14个月内维持在94.0%(95%CI 93.3-94.8,P<0.001)。
以H-ER-O-S方案为目标的POCQI原则通过提高对VAP护理集束的依从性有助于降低VAP发生率。