Schindele Jakob C, Schindele Stephan F
Abteilung für Handchirurgie, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Schweiz.
Oper Orthop Traumatol. 2025 Sep 15. doi: 10.1007/s00064-025-00912-x.
Rheumatoid arthritis (RA) is a chronic inflammatory, immune-mediated disease of the musculoskeletal system that predominantly affects the hands and feet. The introduction of highly potent biologic disease-modifying drugs (bDMARDs) has led to a reduction in severe joint destruction and surgical interventions over the last two decades. Nevertheless, hand surgery remains an essential component of interdisciplinary therapy. Joint-preserving measures such as selective arthroplasty and partial arthrodesis are increasingly being performed today instead of arthrodesis, which was more common in the past. At the same time, the perioperative management of biologics is individually adapted to minimize the risk of infection. The following article draws on more than 30 years of personal experience in the treatment of patients with underlying rheumatic diseases and discusses current treatment recommendations for the hand and wrist.
类风湿关节炎(RA)是一种慢性炎症性、免疫介导的肌肉骨骼系统疾病,主要影响手和脚。在过去二十年中,强效生物疾病改善药物(bDMARDs)的引入减少了严重的关节破坏和手术干预。然而,手部手术仍然是多学科治疗的重要组成部分。如今,诸如选择性关节成形术和部分关节融合术等保留关节的措施越来越多地被采用,而不是过去更常见的关节融合术。同时,生物制剂的围手术期管理会根据个体情况进行调整,以将感染风险降至最低。以下文章借鉴了30多年来治疗患有潜在风湿性疾病患者的个人经验,并讨论了当前针对手和腕部的治疗建议。