Pitkänen J, Lahti A, Sundell B
Scand J Plast Reconstr Surg. 1985;19(3):289-94. doi: 10.3109/02844318509074517.
From 1966 to 1978, 70 patients with carcinoma of the lip were treated at the Division of Plastic Surgery, University Central Hospital, Helsinki. The lip tumour was a squamous cell carcinoma in 64 patients, and a basal cell carcinoma in 6 patients. Of these 70 patients, 24 had radiotherapy as the primary mode of therapy and 46 patients had been treated initially by surgery. The results of surgery were generally good. However, in the group of "simple wedge excision" and in patients who had had radiotherapy as the primary treatment there was a higher incidence of recurrences. In the former group the recurrences were considered to be due to a too narrow angle of excision. We recommend surgery as the primary method of treatment because of the availability of histologically accurate tumour margin assessment, the short rehabilitation period and the good functional results achieved.
1966年至1978年期间,赫尔辛基大学中心医院整形外科共治疗了70例唇部癌患者。其中64例患者的唇部肿瘤为鳞状细胞癌,6例为基底细胞癌。在这70例患者中,24例以放疗作为主要治疗方式,46例最初接受了手术治疗。手术结果总体良好。然而,“单纯楔形切除术”组以及以放疗作为主要治疗方式的患者中,复发率较高。在前一组中,复发被认为是由于切除角度过窄所致。由于能够在组织学上准确评估肿瘤边缘、康复期短且功能效果良好,我们推荐手术作为主要治疗方法。