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Surgery. 2024 Aug;176(2):371-378. doi: 10.1016/j.surg.2024.04.034. Epub 2024 Jun 1.
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Plastic Wound Protector vs Surgical Gauze for Surgical Site Infection Reduction in Open GI Surgery: A Randomized Clinical Trial.塑料伤口保护器与手术纱布在开放式胃肠手术中减少手术部位感染的比较:一项随机临床试验。
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接受腹部手术的糖尿病患者的伤口愈合:一项回顾性研究。

Wound Healing in Diabetic Patients Undergoing Abdominal Surgery: A Retrospective Study.

作者信息

Fadhil Tiba, Batool Amna, Khan Hussain, Farooq Muhammad Shahid

机构信息

General Surgery, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.

Surgery, Fatima Memorial Hospital, Lahore, PAK.

出版信息

Cureus. 2025 Aug 15;17(8):e90132. doi: 10.7759/cureus.90132. eCollection 2025 Aug.

DOI:10.7759/cureus.90132
PMID:40955237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12433574/
Abstract

Background Patients with diabetes mellitus are more likely to develop complications in healing after abdominal surgery. The study aims to compare and evaluate the process of wound healing in diabetic and nondiabetic patients following abdominal surgery. Methods A group of 100 patients underwent elective abdominal surgeries (50 diabetic and 50 nondiabetic). A prospective observational study was performed on these patients. On days 3, 7, and 14, standardized wound healing scores were used to assess the process of wound healing after surgery. The CDC's criteria were used to grade surgical site infections (SSIs) in this study. The factors observed for each sample were wound edema, erythema, discharge, the SSI grade, and the time it took to heal. Results Among the 100 patients who received abdominal surgery, the incidence of SSI was greater in diabetic patients, i.e., 15 (30%) versus five (10%) in nondiabetics. The healing time of >14 days was experienced in 20 (40%) diabetics compared to six (12%) nondiabetics, and dehiscence of wounds was found in six (12%) and two (2%), respectively (p < 0.05). The healing duration of diabetics was also longer (18.1 ± 4.6 vs. 12.5 ± 2.9 days). Grading of infection demonstrated greater Grade I: 10 (20%) vs. 4 (8%), Grade II: 4 (8%) vs. 1 (2%), and Grade III: 1 (2%) vs. 0 (0%). High BMI and diabetes were also major predictors of poor healing. Conclusions Diabetic people had worse postoperative wound healing after abdominal surgery. Glycemic control and perioperative strategies may help improve surgical outcomes.

摘要

背景

糖尿病患者腹部手术后更易出现愈合并发症。本研究旨在比较和评估糖尿病患者与非糖尿病患者腹部手术后的伤口愈合过程。方法:选取100例接受择期腹部手术的患者(50例糖尿病患者和50例非糖尿病患者)。对这些患者进行前瞻性观察研究。在术后第3天、第7天和第14天,使用标准化伤口愈合评分评估术后伤口愈合过程。本研究采用美国疾病控制与预防中心(CDC)的标准对手术部位感染(SSIs)进行分级。观察每个样本的因素包括伤口水肿、红斑、渗出物、SSI分级以及愈合所需时间。结果:在接受腹部手术的100例患者中,糖尿病患者的SSI发生率更高,即糖尿病患者为15例(30%),而非糖尿病患者为5例(10%)。20例(40%)糖尿病患者愈合时间超过14天,而非糖尿病患者为6例(12%),伤口裂开分别为6例(12%)和2例(2%)(p<0.05)。糖尿病患者的愈合持续时间也更长(18.1±4.6天对12.5±2.9天)。感染分级显示,I级更多:10例(20%)对4例(8%),II级:4例(8%)对1例(2%),III级:1例(2%)对0例(0%)。高体重指数和糖尿病也是愈合不良的主要预测因素。结论:糖尿病患者腹部手术后的术后伤口愈合较差。血糖控制和围手术期策略可能有助于改善手术效果。