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儿童急性胰腺炎:15例分析

Acute Pancreatitis in Children: Analysis of 15 Cases.

作者信息

Rkain Maria, Azirar Abir, Karim El Bassil, Hamami Amal, Elouali Aziza, Babakhouya Abdeladim

机构信息

Department of Pediatrics, Faculty of Medicine and Pharmacy of Oujda, Mohammed I University of Oujda, Oujda, MAR.

Pediatric Gastroenterology, Centre Hospitalier Universitaire Mohammed VI de Oujda, Oujda, MAR.

出版信息

Cureus. 2025 Aug 15;17(8):e90167. doi: 10.7759/cureus.90167. eCollection 2025 Aug.

DOI:10.7759/cureus.90167
PMID:40955254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12433681/
Abstract

Acute pancreatitis (AP) in children, although rare, has shown an increasing incidence. This retrospective study analyzed 15 pediatric AP cases over a six-year period from January 2019 to December 2024 at Mohammed VI University Hospital in Oujda, Morocco. The results revealed a male predominance with a sex ratio of 1.5 and a mean age of 8.8 years. The average time from symptom onset to consultation was 3.5 days. The predominant symptom was constant abdominal pain (100%), followed by vomiting (71.4%). Biologically, lipase levels were elevated in 100% of cases, with amylase elevation observed in 14.3%. Radiologically, patients were classified using the Balthazar staging system, with 40% at stage E. Etiologies were mainly idiopathic (26.6%), traumatic (20%), and biliary (20%). All patients received medical treatment, with 6.6% requiring interventional drainage. The majority had favorable outcomes, with 6.6% developing pseudocysts. Diagnosis relies on clinical, biochemical, and radiological criteria, and management is primarily supportive. Early and adequate treatment is essential to prevent complications. Antibiotic use and fluid management protocols require clearer definition.

摘要

儿童急性胰腺炎(AP)虽然罕见,但发病率呈上升趋势。这项回顾性研究分析了2019年1月至2024年12月在摩洛哥乌季达穆罕默德六世大学医院六年期间的15例儿童AP病例。结果显示男性占主导,性别比为1.5,平均年龄为8.8岁。从症状出现到就诊的平均时间为3.5天。主要症状是持续性腹痛(100%),其次是呕吐(71.4%)。生物学上,100%的病例脂肪酶水平升高,14.3%观察到淀粉酶升高。放射学上,使用巴尔萨泽分期系统对患者进行分类,40%处于E期。病因主要是特发性(26.6%)、创伤性(20%)和胆源性(20%)。所有患者均接受了药物治疗,6.6%需要介入引流。大多数患者预后良好,6.6%出现假性囊肿。诊断依赖于临床、生化和放射学标准,治疗主要是支持性的。早期和充分的治疗对于预防并发症至关重要。抗生素的使用和液体管理方案需要更明确的定义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4d3/12433681/a138920dbafd/cureus-0017-00000090167-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4d3/12433681/335b9290ce50/cureus-0017-00000090167-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4d3/12433681/a138920dbafd/cureus-0017-00000090167-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4d3/12433681/335b9290ce50/cureus-0017-00000090167-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4d3/12433681/a138920dbafd/cureus-0017-00000090167-i02.jpg

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Acute pancreatitis in 60 Iranian children: do pediatricians follow the new guidelines in diagnosis and management of acute pancreatitis?60 例伊朗儿童急性胰腺炎:儿科医生在急性胰腺炎的诊断和治疗中遵循新指南吗?
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