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足底黏液软骨样化生1例罕见病例

A Rare Case of Myxochondroid Metaplasia of the Plantar Foot.

作者信息

Elias Michael C, Elias Matthew C, Piliang Melissa P, Tam Christine C

机构信息

Dermatology, Certified Dermatologists, North Royalton, USA.

Dermatology, Cleveland Clinic Foundation, Cleveland, USA.

出版信息

Cureus. 2025 Aug 14;17(8):e90118. doi: 10.7759/cureus.90118. eCollection 2025 Aug.

DOI:10.7759/cureus.90118
PMID:40955273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12433455/
Abstract

We present a case of a 52-year-old male with a slowly enlarging, asymptomatic nodule on his heel diagnosed as myxochondroid metaplasia of the plantar foot. The incidence is rare, as this is only the second case reported since it was first discovered. It is a benign tumor believed to represent a reaction to chronic mechanical stress, presenting as a variably painful, skin-colored nodule on the plantar foot. Histologically, a subepidermal nodule comprised of spindled fibroblasts and cartilaginous elements is seen. It is histopathologically reminiscent of the nuchal fibrocartilaginous pseudotumor as well as the acquired equine digital cushion, two other reactive fibrocartilaginous growths in the neck and a horse's hoof, respectively. Excision is curative.

摘要

我们报告一例52岁男性病例,其足跟部有一个缓慢增大的无症状结节,诊断为足底黏液软骨化生。该发病率罕见,因为这是自首次发现以来报告的第二例病例。它是一种良性肿瘤,被认为是对慢性机械应力的一种反应,表现为足底一个有不同程度疼痛的肤色结节。组织学上,可见一个由梭形成纤维细胞和软骨成分组成的表皮下结节。它在组织病理学上让人联想到项部纤维软骨假瘤以及获得性马指垫,后者分别是颈部和马蹄的另外两种反应性纤维软骨增生。手术切除可治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/051bc0a0f8bf/cureus-0017-00000090118-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/92957093e1d7/cureus-0017-00000090118-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/3651fde93853/cureus-0017-00000090118-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/051bc0a0f8bf/cureus-0017-00000090118-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/92957093e1d7/cureus-0017-00000090118-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/3651fde93853/cureus-0017-00000090118-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae6/12433455/051bc0a0f8bf/cureus-0017-00000090118-i03.jpg

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本文引用的文献

1
A Rare Case of Myxochondroid Metaplasia of the Plantar Foot With Review of Histopathological Mimics.足底罕见黏液软骨样化生病例并复习其组织病理形态学类似物。
Am J Dermatopathol. 2022 Oct 1;44(10):e113-e116. doi: 10.1097/DAD.0000000000002214. Epub 2022 Apr 27.
2
Myxochondroid metaplasia of the plantar foot: a distinctive pseudoneoplastic lesion resembling nuchal fibrocartilaginous pseudotumor and the equine digital cushion.足底的黏液软骨样化生:一种具有特征性的假性肿瘤病变,类似于项韧带纤维软骨假瘤和马数字软垫。
Mod Pathol. 2013 Dec;26(12):1561-7. doi: 10.1038/modpathol.2013.116. Epub 2013 Jun 14.
3
Nuchal fibrocartilaginous pseudotumor: a distinctive soft-tissue lesion associated with prior neck injury.
Am J Surg Pathol. 1997 Jul;21(7):836-40. doi: 10.1097/00000478-199707000-00012.