Hsu Hsiu-Yun, Kuo Li-Chieh, Kuan Ta-Shen, Yang Hsiu-Ching, Pai Ming-Chyi
Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Am J Alzheimers Dis Other Demen. 2024 Jan-Dec;40:15333175241312664. doi: 10.1177/15333175241312664. Epub 2025 Sep 16.
Posterior cortical atrophy (PCA) is a neurodegenerative condition primarily characterized by visuospatial deficits. Research on visual, spatial orientation, and functional impairments in PCA patients is limited. This report explores the impact of occupational therapy on 5 PCA cases with severe visuospatial and functional difficulties over 2 years. Patients, diagnosed through neuropsychological assessments and brain imaging, underwent occupational therapy focusing on cognitive remediation and rehabilitation strategies. Interventions included attention to contextual characteristics and errorless learning to promote independence in self-care. Two patients showed notable improvement on the Loewenstein Occupational Therapy Cognitive Assessment, while 4 demonstrated slight functional gains in activities such as grooming, bathing, dressing, and stair navigation. These findings suggest that cognitive stimulation and training can slow the decline in visuospatial skills and improve daily function. Future studies should incorporate a control group receiving standard occupational therapy and evaluate the long-term impact of these interventions on patients with PCA.
后部皮质萎缩(PCA)是一种主要以视觉空间缺陷为特征的神经退行性疾病。关于PCA患者的视觉、空间定向和功能障碍的研究有限。本报告探讨了职业治疗对5例患有严重视觉空间和功能障碍的PCA患者在2年时间里的影响。通过神经心理学评估和脑部成像确诊的患者接受了以认知矫正和康复策略为重点的职业治疗。干预措施包括关注情境特征和无错误学习,以促进自我护理的独立性。两名患者在洛温斯坦职业治疗认知评估中表现出显著改善,而4名患者在诸如梳理、洗澡、穿衣和上下楼梯等活动中表现出轻微的功能改善。这些发现表明,认知刺激和训练可以减缓视觉空间技能的衰退并改善日常功能。未来的研究应纳入接受标准职业治疗的对照组,并评估这些干预措施对PCA患者的长期影响。