Manatsathit S, Israsena S, Kladcharoen N, Sithicharoenchai P, Roenprayoon S, Suwanakul P
Southeast Asian J Trop Med Public Health. 1985 Sep;16(3):447-52.
Fifty-five Thai patients with chronic diarrhoea were prospectively studied to find out the underlying causes. The aetiology was identified in 38.2%, uncertain in 29.1%, and unknown in 32.7% of the patients. In the group with a definitive aetiologic diagnosis, parasitic and infective causes were commoner than non-infective causes. Amoebiasis and giardiasis were more frequent than expected, such that empirical therapeutic trial with an antiprotozoal may be justified if initial routine investigations fail to uncover the cause of the diarrhoea. No significant clinical features were noted between the infective and the non-infective groups. Overall, repeated stool microscopy using the concentration technique was the most useful single investigation in approaching the chronic diarrhoea problem.
对55例泰国慢性腹泻患者进行了前瞻性研究，以找出潜在病因。38.2%的患者病因明确，29.1%的患者病因不确定，32.7%的患者病因不明。在病因明确诊断的组中，寄生虫和感染性病因比非感染性病因更常见。阿米巴病和贾第虫病比预期更频繁，因此，如果最初的常规检查未能发现腹泻原因，进行抗寄生虫经验性治疗试验可能是合理的。感染组和非感染组之间未观察到明显的临床特征。总体而言，使用浓缩技术反复进行粪便显微镜检查是解决慢性腹泻问题最有用的单项检查。
