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数字减影脊髓造影术中鞘内造影剂密度的优化:在体模中对不同针具特性和注射速率的评估

Optimizing density of intrathecal contrast at digital subtraction myelography: Evaluation of differing needle characteristics and injection rates in a phantom.

作者信息

Malvea Anahita, Chung Emily, Nasralla Mehran, Hendriks Eef J, Farb Richard I

机构信息

Department of Medical Imaging, University of Toronto, Canada.

Department of Medical Imaging, Division of Neuroradiology, University of Toronto, Canada.

出版信息

Interv Neuroradiol. 2025 Sep 16:15910199251375541. doi: 10.1177/15910199251375541.

DOI:10.1177/15910199251375541
PMID:40956898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12440920/
Abstract

Dynamic myelography, performed as digital subtraction myelography or dynamic computed tomography myelography, is crucial in diagnosing intracranial hypotension resulting from a cerebrospinal fluid-venous fistula (CVF). The quality of the myelogram is paramount for accurate diagnosis. Using a phantom, the impact of needle type (Quincke vs. Whitacre), caliber, side-hole position, and rate of injection on the quality of the myelogram was determined. The ideal decubitus myelogram would provide a large volume of a hyperdense contrast within the lateral dependent aspect of the thecal sac, optimally flooding the mouths of the neural foramina and root sleeves where the vast majority of CVFs originate. The results of this study suggest it is exclusively the rate of injection that most predictably dictates the quality of the myelogram in this regard. Specifically, a slow injection rate, on the order of 0.1 mL/s, should be opted for to decrease turbulence, optimize myelogram quality, and thus improve CVF detection in clinical practice.

摘要

动态脊髓造影,以数字减影脊髓造影或动态计算机断层扫描脊髓造影的形式进行,对于诊断由脑脊液 - 静脉瘘(CVF)引起的颅内低压至关重要。脊髓造影的质量对于准确诊断至关重要。使用体模,确定了针型(昆克针与惠塔克针)、口径、侧孔位置和注射速率对脊髓造影质量的影响。理想的卧位脊髓造影应在硬膜囊外侧下垂部位提供大量高密度造影剂,最佳地充盈绝大多数CVF起源处的神经孔和神经根袖的开口。这项研究的结果表明,在这方面,最可预测地决定脊髓造影质量的完全是注射速率。具体而言,应选择约0.1 mL/s的缓慢注射速率,以减少湍流,优化脊髓造影质量,从而在临床实践中改善CVF的检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/77d915e5ef86/10.1177_15910199251375541-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/0d9cdb8ee200/10.1177_15910199251375541-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/a4db6806b702/10.1177_15910199251375541-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/c94e863f7214/10.1177_15910199251375541-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/5e84e72b9858/10.1177_15910199251375541-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/77d915e5ef86/10.1177_15910199251375541-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/0d9cdb8ee200/10.1177_15910199251375541-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/a4db6806b702/10.1177_15910199251375541-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/c94e863f7214/10.1177_15910199251375541-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/5e84e72b9858/10.1177_15910199251375541-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e6/12440920/77d915e5ef86/10.1177_15910199251375541-fig5.jpg

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本文引用的文献

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2
Spontaneous intracranial hypotension due to CSF-venous fistula: Evaluation of renal accumulation of contrast following decubitus myelography and maintained decubitus CT to improve fistula localization.脑脊液-静脉瘘所致自发性颅内低压:卧姿脊髓造影及持续卧姿CT后评估造影剂在肾脏的蓄积以改善瘘口定位
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3
The importance of repeat digital subtraction myelography in the diagnosis of cryptogenic CSF-venous fistula causing spontaneous intracranial hypotension.
重复数字减影脊髓造影在诊断隐源性脑脊液-静脉瘘引起自发性颅内低血压中的重要性。
Interv Neuroradiol. 2021 Oct;27(5):727-732. doi: 10.1177/1591019921991398. Epub 2021 Feb 1.
4
Lateral decubitus digital subtraction myelography to identify spinal CSF-venous fistulas in spontaneous intracranial hypotension.侧卧位数字减影脊髓造影术用于识别自发性颅内低压中的脊髓脑脊液静脉瘘。
J Neurosurg Spine. 2019 Sep 13;31(6):902-905. doi: 10.3171/2019.6.SPINE19487. Print 2019 Dec 1.
5
Spontaneous Intracranial Hypotension: A Systematic Imaging Approach for CSF Leak Localization and Management Based on MRI and Digital Subtraction Myelography.自发性颅内低血压:基于 MRI 和数字减影脊髓造影的 CSF 漏定位和管理的系统影像学方法。
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Do pencil-point spinal needles decrease the incidence of postdural puncture headache in reality? A comparative study between pencil-point 25G Whitacre and cutting-beveled 25G Quincke spinal needles in 320 obstetric patients.在实际操作中,铅笔尖式腰麻针能降低硬膜穿刺后头痛的发生率吗?一项针对320例产科患者,比较25G铅笔尖式Whitacre腰麻针与25G斜口Quincke腰麻针的研究。
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