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合并孤立性凝血因子VII缺乏的艾米安德疝的术前诊断及腹腔镜治疗:一例报告

Preoperative diagnosis and laparoscopic management of Amyand's hernia with isolated factor VII deficiency: A case report.

作者信息

Bajafar Abdulkaream, Mohamed Rawan, Elaagib Malaz, Ali Mohamed

机构信息

Department of General Surgery, East Jeddah Hospital, Jeddah, Saudi Arabia.

Department of General Surgery, East Jeddah Hospital, Jeddah, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2025 Oct;135:111934. doi: 10.1016/j.ijscr.2025.111934. Epub 2025 Sep 12.

DOI:10.1016/j.ijscr.2025.111934
PMID:40957361
Abstract

INTRODUCTION AND IMPORTANCE

Amyand's hernia is a rare condition in which the vermiform appendix herniates through the inguinal canal, with an estimated prevalence of 1 %. Isolated factor VII deficiency is part of a rare group of coagulopathies, with an incidence of 1 in 50,000. To our knowledge, this is the first documented report of Amyand's hernia with isolated factor VII deficiency.

CASE PRESENTATION

We present a 59-year-old male with a 4-month history of progressive right scrotal swelling. Computed tomography revealed herniation of the appendix into the inguinal canal, confirming Amyand's hernia. Routine preoperative laboratory evaluation showed factor VII deficiency. Transabdominal preperitoneal hernia (TAPP) repair was done successfully without appendectomy, as the appendix was not inflamed.

CLINICAL DISCUSSION

Amyand's hernia is often diagnosed intraoperatively, though CT and ultrasonography enable preoperative recognition. Management is typically guided by the Losanoff and Basson classification. The role of prophylactic appendectomy in uninflamed appendices remains debated; in this case it was avoided to preserve a clean surgical field. The factor VII deficiency required perioperative recombinant factor VII replacement, which was successful.

CONCLUSION

Amyand's hernia with isolated factor VII deficiency is rare and has no standard treatment protocol, but we were able to perform surgery safely with appropriate precautions.

摘要

引言与重要性

艾米安德疝是一种罕见病症,即阑尾经腹股沟管疝出,估计患病率为1%。孤立性因子VII缺乏症是一组罕见的凝血病的一部分,发病率为五万分之一。据我们所知,这是首例有记录的合并孤立性因子VII缺乏症的艾米安德疝报告。

病例介绍

我们报告一名59岁男性,有4个月进行性右侧阴囊肿胀病史。计算机断层扫描显示阑尾疝入腹股沟管,确诊为艾米安德疝。术前常规实验室检查显示因子VII缺乏。由于阑尾未发炎,成功实施了经腹腹膜前疝修补术(TAPP),未行阑尾切除术。

临床讨论

艾米安德疝通常在术中诊断,不过CT和超声检查可实现术前识别。治疗通常依据洛萨诺夫和巴森分类法进行指导。对于未发炎阑尾是否进行预防性阑尾切除术仍存在争议;在本病例中,为保持手术视野清洁而避免了该操作。因子VII缺乏症需要围手术期补充重组因子VII,结果成功。

结论

合并孤立性因子VII缺乏症的艾米安德疝很罕见,且没有标准治疗方案,但我们通过采取适当预防措施得以安全地进行手术。

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