解读调控基因组。 - Suppr

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Making sense of the regulatory genome.

出版信息

Nat Rev Genet. 2025 Oct;26(10):651-652. doi: 10.1038/s41576-025-00894-3.

DOI:10.1038/s41576-025-00894-3

PMID:40957945

Abstract

摘要

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本文引用的文献

Predicting the regulatory genome.预测调控基因组。

Nat Rev Genet. 2025 Oct;26(10):659-660. doi: 10.1038/s41576-025-00887-2.

Regulatory genome annotation.调控基因组注释

Nat Rev Genet. 2025 Oct;26(10):661-662. doi: 10.1038/s41576-025-00885-4.

Cis-regulatory elements at cellular resolution.细胞分辨率下的顺式调控元件

Nat Rev Genet. 2025 Oct;26(10):653-654. doi: 10.1038/s41576-025-00882-7.

Is enhancer-driven gene regulation all wrapped up?增强子驱动的基因调控已经完全阐明了吗？

Nat Rev Genet. 2025 Oct;26(10):655-656. doi: 10.1038/s41576-025-00880-9.

Regulatory genomics at biobank scales.生物样本库规模的调控基因组学。

Nat Rev Genet. 2025 Oct;26(10):657-658. doi: 10.1038/s41576-025-00879-2.

Tracing the evolution of sequencing into the era of genomic medicine.追溯测序技术在基因组医学时代的发展历程。

Nat Rev Genet. 2025 Aug 15. doi: 10.1038/s41576-025-00884-5.

Methods and applications of in vivo CRISPR screening.体内CRISPR筛选的方法与应用

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Determining variant effects with pooled prime editing.利用汇集式碱基编辑确定变异效应

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Measuring the effects of regulatory variants in an endogenous context.在内源环境中测量调控变异的影响。

Nat Rev Genet. 2025 Jun 11. doi: 10.1038/s41576-025-00863-w.

Predicting gene expression from DNA sequence using deep learning models.使用深度学习模型从DNA序列预测基因表达。

Nat Rev Genet. 2025 May 13. doi: 10.1038/s41576-025-00841-2.

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