Kwon Yong Jae, Kwon Hyunhee, Ha Suhyeon, Kim Dae Yeon, Cho Yu Jeong, Lee Ju Yeon, Nam So Hyun, Jung Eunyoung
GangNeung Asan Hospital, University of Ulsan College of Medicine, GangNeung, Republic of Korea.
Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Pediatr Surg Int. 2025 Sep 16;41(1):295. doi: 10.1007/s00383-025-06196-3.
Anterior anus (AA) is a congenital anatomical variant with unclear clinical implications and management strategies. This study evaluated the clinical features, associated anomalies, and outcomes of AA in female infants.
This multicenter retrospective cohort study included infants diagnosed with AA between 2020 and 2024 at six tertiary referral centers in South Korea. The clinical characteristics, coexisting anomalies, and outcomes including constipation and urinary tract infections were analyzed.
Among the 64 patients included in this study, 51.6% had a concomitant perineal groove. Congenital heart diseases were the most common coexisting anomaly, occurring in 32 patients. During a mean follow-up of 22.9 months, constipation was observed in 23% of the patients. Urinary tract infections were not observed. The perineal groove resolved spontaneously in 87.9% of cases.
AA is a benign anatomical variant that does not increase the risk of constipation or urinary tract infections. Given the observed association with congenital heart disease, cardiac evaluation should be considered when clinically indicated.
前肛门（AA）是一种先天性解剖变异，其临床意义和处理策略尚不清楚。本研究评估了女婴AA的临床特征、相关异常及结局。
这项多中心回顾性队列研究纳入了2020年至2024年期间在韩国6家三级转诊中心诊断为AA的婴儿。分析了临床特征、并存异常以及包括便秘和尿路感染在内的结局。
本研究纳入的64例患者中，51.6%伴有会阴沟。先天性心脏病是最常见的并存异常，有32例患者出现。在平均22.9个月的随访期间，23%的患者出现便秘。未观察到尿路感染。87.9%的病例中会阴沟自行消退。
AA是一种良性解剖变异，不会增加便秘或尿路感染的风险。鉴于观察到与先天性心脏病有关，临床有指征时应考虑进行心脏评估。
