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银屑病的补骨脂素加长波紫外线疗法：选择合适的治疗方案。

PUVA therapy for psoriasis: choosing a suitable régime.

作者信息

Samuel M, Henry R W, Allen G E, Kelly A M

出版信息

Ulster Med J. 1985 Oct;54(2):196-9.

PMID:4095810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2448121/
Abstract

Three age- and sex-matched groups of 30 patients with chronic plaque psoriasis were treated by photochemotherapy (PUVA). Groups I and II received routine maintenance PUVA therapy at different intervals and Group III had no maintenance treatment. The remission time after the clearance treatment with PUVA is compared with the total cumulative dose of long wave ultraviolet light (UVA). A lower mean dose of UVA (51.0 +/- 1.7 joules/cm(2)) in Group III (no maintenance PUVA) achieved a comparable remission period to that after larger cumulative doses following routine maintenance therapy (87.8 +/- 4.9 and 77.0 +/- 4.1 joules/cm(2) in Groups I and II).

摘要

将30例慢性斑块状银屑病患者按年龄和性别匹配分为三组，接受光化学疗法（补骨脂素加长波紫外线，PUVA）治疗。第一组和第二组以不同间隔接受常规维持性PUVA治疗，第三组不进行维持治疗。比较了PUVA清除治疗后的缓解时间与长波紫外线（UVA）的总累积剂量。第三组（无维持性PUVA）较低的平均UVA剂量（51.0±1.7焦耳/平方厘米）所达到的缓解期，与常规维持治疗后较大累积剂量（第一组和第二组分别为87.8±4.9和77.0±4.1焦耳/平方厘米）后的缓解期相当。

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本文引用的文献

1
Photochemotherapy in the treatment of psoriasis and mycosis fungoides.光化学疗法治疗银屑病和蕈样肉芽肿。
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2
An assessment of the effect of photochemotherapy (PUVA) and UV-B phototherapy in the treatment of psoriasis.光化学疗法（补骨脂素加长波紫外线，PUVA）及中波紫外线光疗法治疗银屑病的疗效评估。
Br J Dermatol. 1981 Dec;105(6):629-39. doi: 10.1111/j.1365-2133.1981.tb00972.x.
3
Retinoids and PUVA in psoriasis.类视黄醇与补骨脂素紫外线A光化学疗法治疗银屑病
Br J Dermatol. 1984 Aug;111(2):247-8. doi: 10.1111/j.1365-2133.1984.tb04056.x.
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Long-term risks of psoralen and UV-A therapy for psoriasis.
Arch Dermatol. 1983 May;119(5):426-31.
5
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.口服甲氧沙林与长波紫外线光化学疗法治疗银屑病
N Engl J Med. 1974 Dec 5;291(23):1207-11. doi: 10.1056/NEJM197412052912301.
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Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial.
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Photochemotherapy for psoriasis remission times. Psoralens and UV-A and combined photochemotherapy with anthralin.光化学疗法治疗银屑病的缓解时间。补骨脂素与紫外线A以及蒽林联合光化学疗法。
Clin Exp Dermatol. 1979 Dec;4(4):477-83. doi: 10.1111/j.1365-2230.1979.tb01644.x.
8
Initial photochemotherapy of psoriasis with orally administered 8-methoxypsoralen and longwave ultraviolet light (PUVA).口服8-甲氧基补骨脂素和长波紫外线（PUVA）对银屑病进行初始光化学疗法。
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9
A randomized, controlled clinical trial comparing photochemotherapy with dithranol in the initial treatment of chronic plaque psoriasis.一项比较光化学疗法与地蒽酚用于慢性斑块状银屑病初始治疗的随机对照临床试验。
Clin Exp Dermatol. 1978 Dec;3(4):339-47. doi: 10.1111/j.1365-2230.1978.tb01512.x.

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