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1981 - 1982年于乌普萨拉对中年人群进行的健康调查结果。糖尿病和心血管疾病的风险因素。

Findings in a health survey of middle-aged subjects in Uppsala 1981-82. Risk factors for diabetes mellitus and cardiovascular disease.

作者信息

Cederholm J

出版信息

Ups J Med Sci. 1985;90(3):201-27. doi: 10.3109/03009738509178479.

DOI:10.3109/03009738509178479
PMID:4095818
Abstract

In a health survey in 1981-82 in the city of Uppsala 819 subjects (443 females and 376 males), 47-54 years old, were examined. A 75 g oral glucose tolerance test OGTT was performed in each subject, and fasting and 2-h venous whole blood glucose values were determined. The 2-h value was somewhat higher in females, 4.7 mmol X l-1, than in males, 4.4 mmol X l-1 (p less than 0.01). Known or probable manifest diabetes was present in 1.9% of all subjects. Glucose values within the limits for WHO criteria of glucose intolerance were found in another 7.1% of all subjects after one OGTT. The rates were similar in both sexes. A history of diabetes in first-degree relatives was noted in 13.2% of all subjects. According to a questionnaire, 1.1% of all subjects had had hospital care for myocardial infarction, 4.7% had angina pectoris and 2.4% had intermittent claudication. The rate of subjects on antihypertensive treatment or with untreated high blood pressure greater than or equal to 170/105 mm Hg was 11.2%; of these only 1.8% had untreated high blood pressure. Of the treated subjects, the treatment was adequate in 82.9%. Obesity, defined as relative body mass index greater than or equal to 120%, was found in 34.0% of all subjects, more frequently in females than in males. The rate of smokers was 28.5%. A comparison was made with the results of a similar health survey of about 2 300 middle-aged men in Uppsala in 1970-73. The prevalence of angina pectoris was higher among the men of the present survey than among those of the 1970-73 survey, which may at least partly be due to differences in methodology. Relative body weight was higher, and fewer men were regularly active during leisure for at least 2-3 h per week in the present study. The rates of hypertension were similar, but fewer men had untreated high blood pressure and more men were on antihypertensive treatment in the present study. There was a lower frequency of smokers in this study.

摘要

1981 - 1982年在瑞典乌普萨拉市开展了一项健康调查,对819名年龄在47至54岁之间的受试者(443名女性和376名男性)进行了检查。对每位受试者进行了75克口服葡萄糖耐量试验(OGTT),并测定了空腹和2小时静脉全血葡萄糖值。女性的2小时血糖值略高于男性,分别为4.7毫摩尔/升和4.4毫摩尔/升(p < 0.01)。所有受试者中,已知或可能患有显性糖尿病的比例为1.9%。在一次OGTT后,另外7.1%的受试者血糖值处于世界卫生组织葡萄糖不耐受标准范围内。男女比例相似。所有受试者中有13.2%的一级亲属有糖尿病病史。根据问卷调查,所有受试者中有1.1%因心肌梗死接受过住院治疗,4.7%患有心绞痛,2.4%患有间歇性跛行。接受抗高血压治疗或未治疗但高血压大于或等于170/105毫米汞柱的受试者比例为11.2%;其中只有1.8%为未治疗的高血压患者。在接受治疗的受试者中,82.9%的治疗是充分的。肥胖定义为相对体重指数大于或等于120%,所有受试者中有34.0%肥胖,女性比男性更常见。吸烟者比例为28.5%。将本次调查结果与1970 - 1973年在乌普萨拉对约2300名中年男性进行的类似健康调查结果进行了比较。本次调查中男性心绞痛的患病率高于1970 - 1973年调查中的男性,这至少部分可能是由于方法学上的差异。在本研究中,相对体重更高,且每周至少有2 - 3小时休闲时间进行规律活动的男性更少。高血压患病率相似,但本研究中未治疗高血压的男性更少,接受抗高血压治疗的男性更多。本研究中吸烟者的频率更低。

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