Wang Wei, Wang Fang, Liu Ping
Department of Otorhinolaryngology, Shaoxing People's Hospital, Shaoxing, Zhejiang Province, China.
Medicine (Baltimore). 2025 Sep 12;104(37):e44344. doi: 10.1097/MD.0000000000044344.
Osteomyelitis of the skull following the endoscopic resection of multiple nasopharyngeal cysts is extremely rare. Postoperative headache, in the absence of fever or ear pain, may no be typically present and could be easily overlooked, potentially leading to a delay in diagnosis and treatment.
In this case report, we present the case of a 57-year-old male patient who developed persistent headache symptoms 1 week after undergoing endoscopic resection of nasopharyngeal cysts under general anesthesia and was diagnosed with skull base osteomyelitis (SBO).
SBO.
After the diagnosis of SBO, the patient was treated with a full course of antibiotics, including 2.0 g ceftriaxone for intravenous infusion for 1 week, 2.5 g of piperacillin sodium and sulbactam for intravenous infusion 12 hours for 2 weeks, and 0.6 g of linezolid tablets for oral administration twice a day for 2 weeks. Under local conditions, endoscopic nasopharyngeal incision and drainage were performed, during which necrotic tissue and pus were removed, and deep tissue secretions were taken.
In the follow-up 6 months at the outpatient clinic after discharge, the patient's headache improved, no complications occurred, and no symptoms of cranial nerve palsy were observed.
Magnetic resonance imaging revealed 3 deep cysts in the nasopharynx. During surgery, when using plasma to resect cysts, it is necessary to avoid excessive exposure or damage to the bone, which would increase the risk of postoperative SBO.
在内镜下切除多个鼻咽囊肿后发生颅骨骨髓炎极为罕见。术后头痛在无发热或耳痛的情况下可能不典型,容易被忽视,可能导致诊断和治疗延迟。
在本病例报告中,我们介绍了一名57岁男性患者,他在全身麻醉下接受内镜下鼻咽囊肿切除术后1周出现持续性头痛症状,被诊断为颅底骨髓炎(SBO)。
SBO。
诊断为SBO后,患者接受了全程抗生素治疗,包括静脉输注2.0g头孢曲松1周,静脉输注2.5g哌拉西林钠舒巴坦12小时,共2周,以及口服0.6g利奈唑胺片,每日2次,共2周。在局部条件下,进行了内镜下鼻咽切开引流,术中清除坏死组织和脓液,并采集深部组织分泌物。
出院后门诊随访6个月,患者头痛改善,未发生并发症,未观察到颅神经麻痹症状。
磁共振成像显示鼻咽部有3个深部囊肿。手术中使用等离子体切除囊肿时,有必要避免过度暴露或损伤骨质,这会增加术后发生SBO的风险。