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USE OF PLATELET-RICH PLASMA IN THE TREATMENT OF ROTATOR CUFF INJURIES: REVIEW OF CLINICAL TRIALS.富血小板血浆在肩袖损伤治疗中的应用:临床试验综述
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本文引用的文献

1
The Biological Effect of Platelet-Rich Plasma on Rotator Cuff Tears: A Prospective Randomized In Vivo Study.富血小板血浆对肩袖撕裂的生物学效应:一项前瞻性随机体内研究。
Int J Mol Sci. 2024 Jul 21;25(14):7957. doi: 10.3390/ijms25147957.
2
Comparative efficacy of platelet-rich plasma (PRP) injection versus PRP combined with vitamin C injection for partial-thickness rotator cuff tears: a randomized controlled trial.富血小板血浆(PRP)注射与 PRP 联合维生素 C 注射治疗部分厚度肩袖撕裂的比较疗效:一项随机对照试验。
J Orthop Surg Res. 2024 Jul 23;19(1):426. doi: 10.1186/s13018-024-04917-3.
3
Leukocyte-Poor Platelet-Rich Plasma as an Adjuvant to Arthroscopic Rotator Cuff Repair Reduces the Retear Rate But Does Not Improve Functional Outcomes: A Double-Blind Randomized Controlled Trial.贫白细胞富血小板血浆作为关节镜肩袖修复的辅助手段可降低再撕裂率,但不能改善功能结局:一项双盲随机对照试验。
Am J Sports Med. 2024 May;52(6):1403-1410. doi: 10.1177/03635465241239062. Epub 2024 Apr 8.
4
Collagen and platelet-rich plasma in partial-thickness rotator cuff injuries. Friends or only indifferent neighbours? Randomised controlled trial.部分厚度肩袖损伤中的胶原蛋白和富含血小板的血浆。朋友还是仅仅是漠不关心的邻居?随机对照试验。
BMC Musculoskelet Disord. 2022 Dec 20;23(1):1109. doi: 10.1186/s12891-022-06089-9.
5
Rotator Cuff Injury and Repair.肩袖损伤与修复。
Semin Musculoskelet Radiol. 2022 Oct;26(5):585-596. doi: 10.1055/s-0042-1756167. Epub 2022 Dec 19.
6
Injection of Leukocyte-Poor Platelet-Rich Plasma for Moderate-to-Large Rotator Cuff Tears Does Not Improve Clinical Outcomes but Reduces Retear Rates and Fatty Infiltration: A Prospective, Single-Blinded Randomized Study.富白细胞血小板血浆注射治疗中等至大型肩袖撕裂不改善临床结果但可降低再撕裂率和脂肪浸润:一项前瞻性、单盲随机研究。
Arthroscopy. 2022 Aug;38(8):2381-2388.e1. doi: 10.1016/j.arthro.2022.02.007. Epub 2022 Mar 3.
7
Platelet-Rich Plasma in Arthroscopic Rotator Cuff Repair: Clinical and Radiological Results of a Prospective Randomized Controlled Trial Study at 10-Year Follow-Up.关节镜下肩袖修复中富血小板血浆:10 年随访前瞻性随机对照试验研究的临床和影像学结果。
Arthroscopy. 2022 Jan;38(1):51-61. doi: 10.1016/j.arthro.2021.05.017. Epub 2021 May 27.
8
Treatment of Rotator Cuff Tears with platelet rich plasma: a prospective study with 2 year follow-up.富血小板血浆治疗肩袖撕裂:一项前瞻性研究,随访 2 年。
BMC Musculoskelet Disord. 2021 May 29;22(1):499. doi: 10.1186/s12891-021-04288-4.
9
Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study.皮质类固醇或富含血小板的血浆注射治疗肩袖肌腱病:一项随机临床试验研究。
J Orthop Surg Res. 2021 May 21;16(1):333. doi: 10.1186/s13018-021-02470-x.
10
Efficacy of Adjuvant Application of Platelet-Rich Plasma After Needle Aspiration of Calcific Deposits for the Treatment of Rotator Cuff Calcific Tendinitis: A Double-Blinded, Randomized Controlled Trial With 2-Year Follow-up.富血小板血浆辅助治疗钙化性冈上肌腱炎经皮穿刺抽吸术后的疗效:一项 2 年随访的双盲、随机对照试验。
Am J Sports Med. 2021 Mar;49(4):873-882. doi: 10.1177/0363546520987579. Epub 2021 Feb 10.

富血小板血浆在肩袖损伤治疗中的应用:临床试验综述

USE OF PLATELET-RICH PLASMA IN THE TREATMENT OF ROTATOR CUFF INJURIES: REVIEW OF CLINICAL TRIALS.

作者信息

Cintra João Paulo Coelho, Ravagnani Hugo Pinhone, do Nascimento Murillo Augusto Ribeiro, Nishimura Henrique de Paula Rodrigues

机构信息

Hospital Santa Casa de Misericordia de Ribeirao Preto, Serviço de Ortopedia e Traumatologia, Ribeirao Preto, Sao Paulo, SP, Brazil.

出版信息

Acta Ortop Bras. 2025 Sep 8;33(4):e290196. doi: 10.1590/1413-785220253304e290196. eCollection 2025.

DOI:10.1590/1413-785220253304e290196
PMID:40958813
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12435861/
Abstract

Rotator cuff injuries occur due to overuse of the shoulder joint, trauma or age-related degeneration, and are aggravated by subacromial lesions and anatomical factors. Symptoms include persistent pain, reduced range of motion and muscle weakness, compromising patients' quality of life. Treatment can be conservative or surgical, and platelet-rich plasma (PRP) has emerged as an alternative to speed up healing and reduce inflammation. The objective was to review the literature on the use of PRP in the treatment of rotator cuff injuries. Clinical trials published in the last 5 years and available in the PUBMED database were selected, based on the following search strategy: (platelet[title] AND rich[title] AND plasma[title]) AND (rotator[title] AND cuff[title]). The 13 studies that responded to the initial search were included in the sample that made up this review. PRP has been shown to be a promising alternative for treating rotator cuff injuries, especially in terms of short-term pain and function. However, its long-term efficacy and its comparison with corticosteroids are still a matter of debate. Therefore, the choice of treatment should be personalized, taking into account the characteristics and goals of each patient.

摘要

肩袖损伤是由于肩关节过度使用、创伤或年龄相关退变引起的,并因肩峰下病变和解剖因素而加重。症状包括持续疼痛、活动范围减小和肌肉无力,会影响患者的生活质量。治疗方法可以是保守治疗或手术治疗,富血小板血浆(PRP)已成为加速愈合和减轻炎症的一种替代方法。目的是综述关于PRP在治疗肩袖损伤中应用的文献。根据以下检索策略,选取过去5年发表在PUBMED数据库中的临床试验:(血小板[标题] AND 富[标题] AND 血浆[标题])AND(肩袖[标题] AND 肩袖[标题])。对初步检索做出回应的13项研究被纳入构成本综述的样本中。PRP已被证明是治疗肩袖损伤的一种有前景的替代方法,特别是在短期疼痛和功能方面。然而,其长期疗效以及与皮质类固醇的比较仍存在争议。因此,治疗选择应因人而异,考虑到每个患者的特点和目标。