Burgos-Sanchez Christian, Bataba Eudoxie, Costello Justin, Bess Daniel, Dedekam Erik
Department of Radiology, Madigan Army Medical Center, 9040A Jackson Ave, Joint Base Lewis-McChord, WA 98431, USA.
Department of Radiology, UT Southwestern Medical Ctr, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Radiol Case Rep. 2025 Apr 24;20(7):3388-3392. doi: 10.1016/j.radcr.2025.03.050. eCollection 2025 Jul.
Moyamoya disease is a rare progressive cerebrovascular condition that affects the internal carotid arteries and their major branches. This leads to the formation of a networks of collateral moyamoya vessels and can cause ischemic or hemorrhagic complications. Moyamoya syndrome is a secondary condition that presents with moyamoya vessels and is associated with other underlying causes including Down syndrome, sickle cell anemia, intracranial atherosclerosis or thyroid disease. In this case report, we discuss a 29-year-old female with Grave's disease who presented with recurrent headaches, acute intermittent numbness and paresthesia. Radiologic evaluation showed multifocal intracranial infarcts and stenosis of the bilateral internal carotid arteries and decreased caliber of the distal anterior circulation. This case highlights the importance of considering MMD/MMS as a differential diagnosis in patients suffering from headaches and/or seizures, especially in the third or fourth decades of life. Prompt diagnosis and management leads to favorable outcomes in patients with moyamoya.
烟雾病是一种罕见的进行性脑血管疾病，影响颈内动脉及其主要分支。这会导致烟雾状侧支血管网络的形成，并可能引发缺血性或出血性并发症。烟雾综合征是一种继发性疾病，表现为烟雾状血管，并与其他潜在病因相关，包括唐氏综合征、镰状细胞贫血、颅内动脉粥样硬化或甲状腺疾病。在本病例报告中，我们讨论了一名患有格雷夫斯病的29岁女性，她出现反复头痛、急性间歇性麻木和感觉异常。影像学评估显示多灶性颅内梗死、双侧颈内动脉狭窄以及远端前循环管径变细。本病例强调了在患有头痛和/或癫痫发作的患者中，尤其是在生命的第三或第四个十年，将烟雾病/烟雾综合征作为鉴别诊断的重要性。对烟雾病患者进行及时诊断和治疗可带来良好的预后。
