一例由弥漫性大B细胞淋巴瘤引起的科莱-西卡尔综合征罕见病例。
A rare case of Collet-Sicard syndrome caused by diffuse large B-cell lymphoma.
作者信息
Jakubik Karol, Szewczyk Anna K, Jeżak Mikołaj, Staśkiewicz Grzegorz, Rejdak Konrad
机构信息
Department of Human Anatomy, Medical University of Lublin, Poland.
Department of Neurology, Medical University of Lublin, Poland.
出版信息
Postep Psychiatr Neurol. 2025 Sep;34(3):216-219. doi: 10.5114/ppn.2025.151809. Epub 2025 Aug 21.
PURPOSE
Collet-Sicard syndrome (CSS) is a neurological condition secondary to various neoplastic and non-neoplastic lesions, manifesting as palsy of the lower cranial nerves. This article aims to disseminate knowledge and share insights into this disorder.
CASE DESCRIPTION
A 58-year-old male presented with a four-month history of progressive dysphagia and dysphonia. Neurological examination revealed cranial nerve IX, X, XI and XII palsy. Imaging demonstrated a focal lesion situated between the internal carotid artery and the jugular vein, ultimately diagnosed as diffuse large B-cell lymphoma. The patient was referred for hematological treatment.
COMMENT
A constellation of symptoms such as dysphagia, hoarseness or dysphonia, and tongue weakness should alert clinicians to the possibility of CSS. Awareness of the characteristic symptoms of CSS is essential for identifying the underlying cause and reducing delays in diagnosis and treatment.
目的
科莱-西卡尔综合征（CSS）是一种继发于各种肿瘤性和非肿瘤性病变的神经系统疾病，表现为下组颅神经麻痹。本文旨在传播关于这种疾病的知识并分享见解。
病例描述
一名58岁男性，有四个月进行性吞咽困难和发音困难病史。神经系统检查显示第IX、X、XI和XII颅神经麻痹。影像学检查显示在颈内动脉和颈静脉之间有一个局灶性病变，最终诊断为弥漫性大B细胞淋巴瘤。该患者被转诊接受血液学治疗。
评论
吞咽困难、声音嘶哑或发音困难以及舌肌无力等一系列症状应提醒临床医生注意CSS的可能性。了解CSS的特征性症状对于确定潜在病因以及减少诊断和治疗延迟至关重要。
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