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农场动物冠状病毒:解决之道在于疫苗。

Farm animal coronaviruses: the solution is in vaccines.

作者信息

Kondakova Olga, Tsybina Anna, Evtushenko Ekaterina, Ryabchevskaya Ekaterina, Granovskiy Dmitriy, Kovalenko Angelina, Arkhipenko Marina, Nikitin Nikolai, Karpova Olga

机构信息

Department of Virology, Lomonosov Moscow State University, Moscow, Russia.

出版信息

Vet Q. 2025 Dec;45(1):1-29. doi: 10.1080/01652176.2025.2556494. Epub 2025 Sep 17.

Abstract

RNA-containing coronaviruses are widespread in nature and can infect a number of vertebrates. Animals are potential sources of human coronaviruses diseases, and interspecies infection by animal coronaviruses has been recorded several times. Such a transmission may have caused the COVID-19 pandemic. The study and control of the spread of farm animals' coronavirus infections is very important, due to the constant close contact between humans and farm animals. Vaccination remains the key to preventing animal diseases and limiting the further spread and transmission of coronavirus infections among poultry and livestock. This review considers coronavirus infections in farm animals, which pose a serious challenge to animal husbandry, and their zoonotic potential and epidemiological features. The review also discusses current vaccines and their limitations, as well as the latest developments and trends in veterinary vaccines aimed at preventing coronavirus infections in poultry and livestock.

摘要

含RNA的冠状病毒在自然界广泛存在,可感染多种脊椎动物。动物是人类冠状病毒疾病的潜在来源,动物冠状病毒的种间感染已有多次记录。这种传播可能导致了新冠疫情。由于人类与家畜持续密切接触,研究和控制家畜冠状病毒感染的传播非常重要。接种疫苗仍然是预防动物疾病以及限制冠状病毒在家禽和家畜中进一步传播的关键。本综述探讨了给畜牧业带来严峻挑战的家畜冠状病毒感染,及其人畜共患病潜力和流行病学特征。综述还讨论了现有疫苗及其局限性,以及旨在预防家禽和家畜冠状病毒感染的兽用疫苗的最新进展和趋势。

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