Påhlman L, Glimelius B, Enblad P
Acta Chir Scand. 1985;151(8):685-93.
Between January 1980 and December 1982, 221 patients with rectal or rectosigmoid carcinoma were admitted from a defined population to one department of surgery in Sweden. In addition, all patients with a rectal tumour were traced in the population, and in this way 83 additional cases were recorded. A total of 304 malignant lesions were diagnosed and 279 (92%) of them were adenocarcinoma. The surgical curability rate in this unselected material of adenocarcinoma of the rectum and rectosigmoid, defined as the proportion of patients operated upon for cure with respect to both local radicality of surgery and absence of indications of disseminated disease, was 60%. Age (greater than or less than 80 years) but not sex had a major influence on the rate of surgical curability. Weight loss and pain, and also more than two tumour-related symptoms at presentation, were more common among patients with noncurable disease. A short diagnostic delay correlated to a more favourable tumour stage.
1980年1月至1982年12月期间，瑞典某外科科室从特定人群中收治了221例直肠或直肠乙状结肠交界处癌患者。此外，还对该人群中所有直肠肿瘤患者进行了追踪，通过这种方式又记录了83例病例。共诊断出304例恶性病变，其中279例（92%）为腺癌。在这一未经挑选的直肠和直肠乙状结肠腺癌病例材料中，手术治愈率（定义为就手术的局部根治性和无播散性疾病迹象而言接受根治性手术的患者比例）为60%。年龄（大于或小于80岁）而非性别对手术治愈率有重大影响。体重减轻和疼痛，以及就诊时出现两种以上与肿瘤相关的症状，在无法治愈的疾病患者中更为常见。诊断延迟短与更有利的肿瘤分期相关。
