Masroor Sheerin, Rafiquee M Z A, Kumar Ajay, Mobin Mohd, Dagdag Omar, Berisha Avni, Khan Mohammad Ehtisham
Department of Chemistry, A.N. College, Patliputra University, Patna, 800013, Bihar, India.
Faculty of Engineering and Technology, Department of Applied Chemistry, Aligarh Muslim University, Aligarh, 202002, UP, India.
Odontology. 2025 Sep 17. doi: 10.1007/s10266-025-01192-4.
Dental implants are continuously exposed to aggressive oral conditions that can trigger corrosion and compromise their long-term success. In the present work, findings highlight the potential of surfactant nanocomposities (NCs), sodium dodecyl sulfate (SDS) with the titanium oxide (TiO₂) nanoparticals (NPs), which were evaluated as corrosion inhibitors using mild steel as a model substrate in artificial saliva. Electrochemical impedance spectroscopy (EIS) and open circuit potential (OCP) measurements revealed that the SDS-TiO₂ system achieved markedly higher inhibition efficiency than SDS alone, owing to strong adsorption and stable inhibitor-surface interactions. Structural characterization confirmed nanoscale particle size and stability. Transmission electron microscopy (TEM) confirmed nanoscale dimensions (13.9-28.6 nm) and and zeta-sizer analysis revealed a single sharp peak with an approximate size of 17 nm with good stability, supporting its effective performance. The high E value ( - 2585.50 kcal/mol) for the SDS-TiO NCs system reflects the greater stability (inhibitor/surface interaction) and consequently increases their inhibition efficiencies. Statistical analysis (ANOVA, p < 0.05) further validated the significant improvement in resistance parameters with SDS-TiO₂. Computational modeling (DFT, Monte Carlo (MC), and Molecular Dynamics (MD) simulations) corroborated experimental findings by demonstrating the strong binding affinity of the inhibitor system adsorbed on the surface of Fe (110) by a horizontal orientation. While mild steel was employed as a surrogate, these results highlight the translational promise of SDS-TiO₂ NCs for enhancing corrosion resistance in dental implant environments. Future validation of the present findings on clinically relevant alloys (CP-Ti and Ti-6Al-4 V) is essential to confirm the translational potential of SDS-TiO₂ systems for real-world dental implant applications. This addition strengthens the clinical anchoring of the study by outlining a clear direction for future research.
牙科植入物不断暴露于具有侵蚀性的口腔环境中，这可能引发腐蚀并影响其长期使用效果。在本研究中，研究结果突出了表面活性剂纳米复合材料（NCs），即十二烷基硫酸钠（SDS）与二氧化钛（TiO₂）纳米颗粒（NPs）的潜力，它们在人工唾液中以低碳钢作为模型基材被评估为缓蚀剂。电化学阻抗谱（EIS）和开路电位（OCP）测量表明，由于强烈的吸附作用和稳定的抑制剂 - 表面相互作用，SDS - TiO₂ 体系比单独的 SDS 具有显著更高的抑制效率。结构表征证实了纳米级粒径和稳定性。透射电子显微镜（TEM）确认了纳米级尺寸（13.9 - 28.6 纳米），并且zeta 粒度分析仪分析显示有一个单一的尖锐峰，近似尺寸为 17 纳米，稳定性良好，支持其有效性能。SDS - TiO NCs 体系的高 E 值（ - 2585.50 千卡/摩尔）反映了更高的稳定性（抑制剂/表面相互作用），从而提高了它们的抑制效率。统计分析（方差分析，p < 0.05）进一步验证了 SDS - TiO₂ 使电阻参数有显著改善。计算建模（密度泛函理论（DFT）、蒙特卡罗（MC）和分子动力学（MD）模拟）通过证明抑制剂体系以水平取向吸附在 Fe(110)表面的强结合亲和力，证实了实验结果。虽然使用低碳钢作为替代物，但这些结果突出了 SDS - TiO₂ NCs 在增强牙科植入物环境中耐腐蚀性方面的转化前景。未来对临床相关合金（CP - Ti 和 Ti - 6Al - 4V）上本研究结果的验证对于确认 SDS - TiO₂ 体系在实际牙科植入物应用中的转化潜力至关重要。这一补充通过为未来研究勾勒出明确方向，加强了该研究的临床基础。
