Explorative studies on karyometric frequency distributions. II. Approximation using normally distributed curves versus median interpolation.

An approximation using normally distributed curves and a median interpolation were applied to frequency distributions of nuclear size with one maximum. Both methods gave the same results as far as the positions of the curves on the axis of nuclear volume classes were concerned. Further detailed information on the course of the curves by the median interpolation, however, may be falsified by artificial differences due to the interpolation.