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颅颈交界区巨大神经鞘瘤的后路切除术:病例系列

Posterior Approach Resection of Giant Schwannomas at the Craniovertebral Junction: A Case Series.

作者信息

Ntsambi Glennie, Maoneo Israël A, Ziko Punga, Kabongo Jean-Richard, Kutoloka Simon, Tshiunza Chérubin, Kasereka Kamabu Larrey, Lebwaze Bienvenu, Chirimwami Raphael, Sanduku Dieudonné, Beltchika Antoine

机构信息

Neurosurgery, University of Kinshasa, Kinshasa, COD.

Neurosurgery, University of Kisangani, Kisangani, COD.

出版信息

Cureus. 2025 Sep 15;17(9):e92338. doi: 10.7759/cureus.92338. eCollection 2025 Sep.

Abstract

Tumors of the craniovertebral junction (CVJ) are rare and present a major surgical challenge due to the anatomical complexity of the region. We report three cases that were admitted and operated on in our department. All three patients presented with motor deficits and bladder-sphincter dysfunction. In the first case, MRI revealed a grossly ovoid tumor measuring 30 x 28 mm, located anterolaterally to the right of the cervical spinal cord at the level of the C2 vertebral body, extending anteriorly beyond the arch of C1. The second patient's contrast-enhanced MRI showed an intradural extramedullary lesion measuring 31 x 27 mm at the C2-C3 level. In the third case, imaging demonstrated spinal cord compression at the C1-C2 level due to a mass measuring 35 x 26 mm in the extradural and extramedullary space, with spontaneous signal located anterior to the dural sac. All patients underwent posterior decompression. Tumor excision was performed under a neurosurgical microscope following C2 laminectomy and partial resection of the posterior arch of C1 in all three cases. Histopathological examination of the resected specimens confirmed the diagnosis of schwannomas. Postoperative outcomes were uneventful, and all patients showed improvement following physiotherapy sessions. This case series highlights the surgical complexity of the posterior approach to CVJ tumors, particularly giant schwannomas, and demonstrates the favorable postoperative course following complete resection.

摘要

颅颈交界区(CVJ)肿瘤较为罕见,由于该区域解剖结构复杂,手术面临重大挑战。我们报告了在我科收治并接受手术的三例病例。所有三名患者均出现运动功能障碍和膀胱括约肌功能障碍。第一例患者,MRI显示一个大致呈椭圆形的肿瘤,大小为30×28mm,位于C2椎体水平颈脊髓右侧前外侧,向前延伸至C1弓之外。第二例患者的增强MRI显示在C2 - C3水平有一个31×27mm的硬脊膜内髓外病变。第三例患者,影像学显示C1 - C2水平脊髓受压,原因是硬膜外和髓外间隙有一个大小为35×26mm的肿块,硬脊膜囊前方有自发信号。所有患者均接受了后路减压手术。在所有三例病例中,均在C2椎板切除和C1后弓部分切除后,在神经外科显微镜下进行肿瘤切除。对切除标本的组织病理学检查确诊为神经鞘瘤。术后情况平稳,所有患者在接受物理治疗后均有改善。该病例系列突出了CVJ肿瘤后路手术的复杂性,尤其是巨大神经鞘瘤,并展示了完整切除后良好的术后病程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7cc/12439001/f4df16f49ec0/cureus-0017-00000092338-i01.jpg

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