Lindell O, Lehtonen T
Ann Chir Gynaecol. 1985;74(6):288-93.
During a 17-year-period from 1967 to 1983, 110 total cystectomies for transitional cell bladder cancer have been performed in our clinic. During the postcystectomy period, upper urinary tract urothelial cancer developed in seven patients (6.4%). In every case a multifocal, low stage transitional cell cancer had been found in the bladder. The time between the cystectomy and discovery of the upper tract tumour varied from less than three months to almost 13 years. In five cases the first sign of occurrence of the tumour was malignant conduit urine cytology, in two macroscopic haematuria with subsequent malignant cells in urine. In one patient bilateral renal pelvic tumours were found. Five patients could be surgically treated. The need for regular conduit urine cytological studies at short intervals in patients with multifocal low stage and high grade transitional cell carcinoma in the cystectomy specimen is emphasised.
在1967年至1983年的17年期间，我们诊所共为110例移行细胞膀胱癌患者实施了全膀胱切除术。在膀胱切除术后，7例患者（6.4%）发生了上尿路尿路上皮癌。每例患者的膀胱中均发现有多灶性、低分期的移行细胞癌。膀胱切除术后至发现上尿路肿瘤的时间间隔从不到三个月至近13年不等。5例患者肿瘤出现的首个迹象是导尿管尿液细胞学检查呈恶性，2例患者先是出现肉眼血尿，随后尿液中发现恶性细胞。1例患者双侧肾盂肿瘤被发现。5例患者可接受手术治疗。强调了对于膀胱切除标本中存在多灶性、低分期和高级别移行细胞癌的患者，需要每隔较短时间定期进行导尿管尿液细胞学检查。
