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[重症监护患者肠外营养期间的高氨血症]

[Hyperammonemia during parenteral nutrition of intensive-care patients].

作者信息

Hackl J M, Hengl W, Rumpl E, Geir F, Rosmanith P, Jarosch E

出版信息

Infusionsther Klin Ernahr. 1977 Aug;4(4):212-6.

PMID:409669
Abstract

Metabolic features of parenteral feeding with conventional amino acid solutions were examined in 47 patients over a long period. 30 patients were kept alive by artificial respiration. The metabolic parameters ammonium, blood urea nitrogen, GOT, alkaline phosphatase were carried out, in 6 patients the pattern of amino acids was analysed. All patients showed a significant increase of ammonium during the course of parenteral feeding. The amino acids demonstrated pattern of imbalance. The other other parameters were not changed significantly. Traumatic, hypoxic or toxic liver damage might influence the reduction of liver function.

摘要

对47例患者长期使用传统氨基酸溶液进行肠外营养的代谢特征进行了研究。30例患者依靠人工呼吸维持生命。测定了代谢参数铵、血尿素氮、谷草转氨酶、碱性磷酸酶,对6例患者的氨基酸模式进行了分析。所有患者在肠外营养过程中铵均显著升高。氨基酸显示出失衡模式。其他参数无明显变化。创伤性、低氧性或中毒性肝损伤可能影响肝功能的降低。

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