Salah Maryam, Rimani Mouna, Benjelloun Laïla, Taleb Bouchra
Department of Oral Surgery, Faculty of Dental Medicine, Mohamed V University in Rabat, Rabat, Morocco.
Department of Pathological Anatomy Hassan, Rabat, Morocco.
Int J Surg Case Rep. 2025 Oct;135:111929. doi: 10.1016/j.ijscr.2025.111929. Epub 2025 Sep 11.
Nodular fasciitis is a rare, benign, rapidly growing, self-limited myofibroblastic/fibroblastic pseudotumor that often mimics sarcomas, making its diagnosis particularly challenging. While it typically occurs in the subcutaneous tissues of the trunk and extremities, intraoral presentation is extremely uncommon.
We report a rare case of oral nodular fasciitis in a 10-year-old patient who presented with delayed eruption of the right lower premolars and a firm, rapidly enlarging, painless swelling in the corresponding region. An excisional biopsy was performed, followed by immunohistochemical analysis, which confirmed the diagnosis of nodular fasciitis.
Due to its clinical and histopathological resemblance to malignant lesions, nodular fasciitis can easily be misdiagnosed, potentially leading to overtreatment. Recognizing its key features is essential to avoid unnecessary and invasive procedures, especially in pediatric patients.
This case highlights the importance of considering nodular fasciitis in the differential diagnosis of rapidly growing soft tissue masses in the oral cavity, particularly in children.
结节性筋膜炎是一种罕见的、良性的、生长迅速的、自限性的肌成纤维细胞/纤维母细胞性假瘤,常酷似肉瘤,其诊断极具挑战性。虽然它通常发生于躯干和四肢的皮下组织,但口腔内表现极为罕见。
我们报告一例10岁患者的罕见口腔结节性筋膜炎病例,该患者表现为右下前磨牙萌出延迟,且在相应区域有一个质地坚硬、迅速增大的无痛性肿胀。进行了切除活检,随后进行免疫组织化学分析,确诊为结节性筋膜炎。
由于其临床和组织病理学表现与恶性病变相似,结节性筋膜炎很容易被误诊,可能导致过度治疗。认识其关键特征对于避免不必要的侵入性操作至关重要,尤其是在儿科患者中。
本病例强调了在口腔快速生长的软组织肿块,尤其是儿童患者的鉴别诊断中考虑结节性筋膜炎的重要性。