Sherrin Safiya, Kochhar Jasmine Kaur, Mustafa Wafabi, Batham Kartik
Department of Critical Care Medicine, Dayanand Medical College Hospital, Ludhiana, Punjab, India.
Department of Anaesthesiology, Goa Medical College Hospital, Bambolim, Goa, India.
Int J Crit Illn Inj Sci. 2025 Jul-Sep;15(3):132-135. doi: 10.4103/ijciis.ijciis_44_25. Epub 2025 Sep 11.
Boerhaave's syndrome (BS), or spontaneous esophageal perforation, is a rare and life-threatening condition. Despite advancements in medical and surgical management, BS carries a high mortality rate, up to 50%, and presents significant diagnostic and therapeutic challenges. Management options include both surgical and nonoperative approaches, with the Pittsburgh score providing a useful tool for predicting outcomes and guiding treatment. Complications such as mediastinitis and sepsis are common. This review explores the demographics, risk factors, clinical presentation, diagnostic modalities, and management strategies for BS. Furthermore, it stresses the importance of early diagnosis and individualized treatment to improve the outcomes in patients with BS.
博雷尔哈夫综合征（BS），即自发性食管穿孔，是一种罕见且危及生命的疾病。尽管在医疗和手术管理方面取得了进展，但BS的死亡率仍然很高，高达50%，并带来了重大的诊断和治疗挑战。治疗选择包括手术和非手术方法，匹兹堡评分提供了一个预测预后和指导治疗的有用工具。纵隔炎和败血症等并发症很常见。本综述探讨了BS的人口统计学、危险因素、临床表现、诊断方式和管理策略。此外，它强调了早期诊断和个体化治疗对改善BS患者预后的重要性。
