Trimble A S, Morch J E, Froggatt G M, Metni F N
Can Med Assoc J. 1970 Oct 24;103(9):911-4.
Twenty-seven adult patients with the cyanotic type of tetralogy of Fallot had total intracardiac repair during the past five years at the Toronto General Hospital. Twenty-one of 27 patients (77%) had had a previous shunting operation performed five to 21 years prior to the total intracardiac repair. Seventeen of 21 (81%) of these anastomoses were patent at the time of the total intracardiac repair. The hospital mortality was 11% and was attributable to hemorrhage - a well-recognized problem in adult tetralogy, due to excessive collateral circulation. All 24 surviving patients followéd up from six months to five years showed marked clinical improvement, with disappearance of the cyanosis and reduction in acne and clubbing. Permanent heart block has not occurred. Late hemodynamic studies showed a significant persisting shunt in two out of 16 or 12%.
在过去五年中，27例法洛四联症青紫型成年患者在多伦多综合医院接受了全心脏内修复手术。27例患者中有21例（77%）在全心脏内修复手术前5至21年曾接受过分流手术。在全心脏内修复手术时，这些吻合口中的17例（81%）仍保持通畅。医院死亡率为11%，原因是出血——这是成年法洛四联症中一个公认的问题，是由于过度的侧支循环所致。所有24例存活患者接受了6个月至5年的随访，结果显示临床症状明显改善，紫绀消失，痤疮和杵状指减轻。未发生永久性心脏传导阻滞。后期血流动力学研究显示，16例中有2例（12%）存在明显持续分流。
