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一位有减肥手术史患者的眼部并发症

Ocular complications in a patient with history of bariatric surgery.

作者信息

Mora Correa Jose Miguel, Humayun Arslon, Schwartz Stephen G, Martinez Jaime D

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, 33116, USA.

Georgetown University School of Medicine, 3900 Reservoir Rd NW, Washington, DC, 20007, USA.

出版信息

Am J Ophthalmol Case Rep. 2025 Sep 1;40:102420. doi: 10.1016/j.ajoc.2025.102420. eCollection 2025 Dec.

Abstract

PURPOSE

This case report aims to highlight the potential for severe ocular complications due to vitamin A deficiency (VAD) following bariatric surgery, emphasizing the importance of long-term nutritional monitoring and compliance. We present a case report of corneal ulceration and ocular surface keratinization occurring eight years post-biliopancreatic diversion with duodenal switch (BPD-DS) and discuss its management in the context of limited access to intramuscular vitamin A therapy.

OBSERVATIONS

VAD can present years after bariatric surgery and cause severe ocular complications. In this case, inconsistent multivitamin intake led to xerophthalmia and progressive vision loss, thus highlighting the importance of long-term adherence to supplementation in patients with a history of bariatric surgery. Due to a nationwide shortage of intramuscular vitamin A at the time, high-dose oral therapy was used. Despite being well tolerated, the condition progressed to the point of requiring surgical intervention. This case highlights the importance of early detection, timely treatment, and long-term nutritional monitoring in bariatric patients to prevent irreversible vision loss.

CONCLUSIONS AND IMPORTANCE

VAD can present years after bariatric surgery and cause serious ocular risks. While oral supplementation showed potential, it was insufficient to prevent surgical intervention. This case report aims to raise awareness of post-surgical risks to vision and highlight the importance of long-term nutritional monitoring and early diagnosis in patients with a history of bariatric surgery.

摘要

目的

本病例报告旨在强调减肥手术后因维生素A缺乏(VAD)导致严重眼部并发症的可能性,强调长期营养监测和依从性的重要性。我们报告一例胆胰分流十二指肠转位术(BPD-DS)八年后发生角膜溃疡和眼表角化的病例,并在难以获得肌肉注射维生素A治疗的情况下讨论其治疗方法。

观察结果

VAD可在减肥手术后数年出现并导致严重的眼部并发症。在本病例中,多种维生素摄入不规律导致干眼症和视力逐渐丧失,从而凸显了减肥手术史患者长期坚持补充维生素的重要性。由于当时全国范围内肌肉注射维生素A短缺,采用了高剂量口服治疗。尽管耐受性良好,但病情仍发展到需要手术干预的程度。本病例强调了减肥患者早期发现、及时治疗和长期营养监测以防止不可逆视力丧失的重要性。

结论与重要性

VAD可在减肥手术后数年出现并导致严重的眼部风险。虽然口服补充剂显示出一定潜力,但不足以避免手术干预。本病例报告旨在提高对术后视力风险的认识,并强调减肥手术史患者长期营养监测和早期诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe4e/12445224/19c69dc87e92/gr1.jpg

相似文献

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Ocular complications in a patient with history of bariatric surgery.一位有减肥手术史患者的眼部并发症
Am J Ophthalmol Case Rep. 2025 Sep 1;40:102420. doi: 10.1016/j.ajoc.2025.102420. eCollection 2025 Dec.

本文引用的文献

6
Vitamin A deficiency-related retinopathy after bariatric surgery.
Graefes Arch Clin Exp Ophthalmol. 2012 Jun;250(6):941-3. doi: 10.1007/s00417-011-1715-8. Epub 2011 Jun 9.
9
Gastrointestinal and nutritional complications after bariatric surgery.减肥手术后的胃肠道及营养并发症。
Am J Gastroenterol. 2007 Nov;102(11):2571-80; quiz 2581. doi: 10.1111/j.1572-0241.2007.01421.x. Epub 2007 Jul 19.

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