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使用鼻唇沟皮瓣修复基底细胞癌切除术后右侧鼻翼全层缺损:一种单阶段功能性方法

Reconstruction of a Full-Thickness Right Nasal Ala Defect After Basal Cell Carcinoma Excision Using a Nasolabial Flap: A Single-Stage and Functional Approach.

作者信息

Dorantes-Millan Guillermo Sergio, Puntos-Guizar Cristina Lizbeth, Rodriguez-Ramirez Roberto, Guillen-Morales Uriel, Escobar-Rios Luis Eduardo

机构信息

Surgery, Hospital General Dr. Fernando Quiroz Gutierrez, Mexico City, MEX.

Dermatology, Centro Medico Nacional 20 De Noviembre, Mexico City, MEX.

出版信息

Cureus. 2025 Aug 20;17(8):e90602. doi: 10.7759/cureus.90602. eCollection 2025 Aug.

DOI:10.7759/cureus.90602
PMID:40978852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12448567/
Abstract

Basal cell carcinoma (BCC) is the most prevalent form of non-melanoma skin cancer, involving exposed areas such as the nose. Its location in this anatomically and aesthetically sensitive region poses significant diagnostic and therapeutic challenges, requiring a balance between complete tumor removal and preservation of nasal function and appearance. We present the case of a 64-year-old female cleaning worker with an eight-year history of a gradually enlarging lesion on the right nasal ala, which was diagnosed as a micronodular BCC following biopsy. The micronodular BCC is associated with more aggressive behavior and a higher risk of recurrence. This is why wider surgical margins and careful management are necessary in this type of disease to ensure complete tumor eradication. The patient underwent surgical excision with a 5 mm margin, including the full thickness of the nasal ala. Immediate reconstruction was successfully carried out using a nasolabial flap, a versatile local flap renowned for its excellent match in color, texture, and thickness to the nasal skin, along with its reliable vascular supply and minimal donor site morbidity. Histopathological examination showed free-margin, complete tumor resection and no lymphovascular or perineural invasion. The patient's postoperative evolution was uneventful, with no flap-related complications. At the two-month follow-up, the surgical site had healed with a scar that was discreetly camouflaged within the natural nasolabial fold, preserving nasal contour and facial symmetry. This case highlights the functional and cosmetic benefits of the nasolabial flap for full-thickness nasal ala defect reconstruction, as timely reconstruction of the defect using local flaps not only enhances the functional and cosmetic outcomes but also results in better patient quality of life.

摘要

基底细胞癌(BCC)是非黑素瘤皮肤癌最常见的形式,常累及如鼻子等暴露部位。其位于这个在解剖学和美学上都很敏感的区域,给诊断和治疗带来了重大挑战,需要在完全切除肿瘤与保留鼻腔功能和外观之间取得平衡。我们报告一例64岁女性清洁工人的病例,其右侧鼻翼有一个逐渐增大的病灶,病史长达八年,活检后被诊断为微结节型基底细胞癌。微结节型基底细胞癌具有更具侵袭性的行为和更高的复发风险。这就是为什么对于这类疾病需要更宽的手术切缘和仔细的处理,以确保完全根除肿瘤。患者接受了切缘为5毫米的手术切除,包括鼻翼全层。立即使用鼻唇瓣成功进行了重建,鼻唇瓣是一种多功能局部皮瓣,以其在颜色、质地和厚度上与鼻皮肤的出色匹配、可靠的血供以及最小的供区并发症而闻名。组织病理学检查显示切缘无肿瘤残留,肿瘤完全切除,无淋巴管或神经周围侵犯。患者术后恢复顺利,无皮瓣相关并发症。在两个月的随访中,手术部位已愈合,瘢痕隐匿于自然鼻唇沟内,保留了鼻腔轮廓和面部对称性。该病例突出了鼻唇瓣用于鼻翼全层缺损重建在功能和美容方面的益处,因为使用局部皮瓣及时修复缺损不仅能提高功能和美容效果,还能改善患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/ca0c5ccc0b57/cureus-0017-00000090602-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/b8c286d6a33a/cureus-0017-00000090602-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/37e0c061a2fb/cureus-0017-00000090602-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/d41ac8187d8e/cureus-0017-00000090602-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/ca0c5ccc0b57/cureus-0017-00000090602-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/b8c286d6a33a/cureus-0017-00000090602-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/37e0c061a2fb/cureus-0017-00000090602-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/d41ac8187d8e/cureus-0017-00000090602-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3151/12448567/ca0c5ccc0b57/cureus-0017-00000090602-i04.jpg

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本文引用的文献

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Single-Stage Reconstruction of Nasal Columella Using Bilateral Nasolabial Flaps.
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2
Immediate local flap versus skin graft reconstruction after standard excision of basal cell carcinoma of the nose.鼻基底细胞癌标准切除术后即时局部皮瓣与皮肤移植重建的比较
JPRAS Open. 2025 Mar 25;44:364-374. doi: 10.1016/j.jpra.2025.03.017. eCollection 2025 Jun.
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Let's Twist Again: Nasolabial Turnover Flap for Full-thickness Aesthetical Nasal Ala Reconstruction.再次扭转:鼻唇翻转皮瓣用于全层美学鼻翼重建
Plast Reconstr Surg Glob Open. 2024 Sep 5;12(9):e6128. doi: 10.1097/GOX.0000000000006128. eCollection 2024 Sep.
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Aesthetic Reconstruction Based on Facial Subunit Principle for Basal Cell Carcinoma of the Face: A Retrospective Analysis.基于面部亚单位原则的面部基底细胞癌美学重建:一项回顾性分析
Cureus. 2024 Mar 24;16(3):e56826. doi: 10.7759/cureus.56826. eCollection 2024 Mar.
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Tunneled Island Flaps for the Reconstruction of Nasal Defects: A 21-Case Series.用于鼻缺损修复的隧道岛状皮瓣:21例病例系列
J Clin Med. 2023 Dec 2;12(23):7473. doi: 10.3390/jcm12237473.
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