Kozmane Salma, Baybay Hanane, Tadlaoui Aya, Douhi Zakia, Mernissi FatimaZahra
Dermatology Department, Hassan II University Hospital, Fez, MAR.
Cureus. 2025 Aug 18;17(8):e90426. doi: 10.7759/cureus.90426. eCollection 2025 Aug.
Xanthelasmoid mastocytosis (XM) is a rare form of diffuse cutaneous mastocytosis whose clinical presentation may resemble multiple juvenile xanthogranulomas. We report the case of a two-year-old child who presented with multiple yellowish papules and nodules, with a firm to elastic consistency, symmetrically distributed over the face, the base of the neck, trunk, and limbs. Dermoscopy and histology confirmed the diagnosis of XM. The patient was successfully treated with H1-antihistamines and high-potency topical corticosteroids. This case highlights the importance of considering XM as a rare variant of diffuse cutaneous mastocytosis that may be confused with multiple juvenile xanthogranulomas.
黄瘤样肥大细胞增多症（XM）是一种罕见的弥漫性皮肤肥大细胞增多症，其临床表现可能类似于多发性幼年黄色肉芽肿。我们报告了一例两岁儿童病例，该患儿面部、颈部基部、躯干和四肢对称分布有多个淡黄色丘疹和结节，质地硬至有弹性。皮肤镜检查和组织学检查确诊为XM。该患者通过H1抗组胺药和高效外用皮质类固醇成功治愈。该病例强调了将XM视为弥漫性皮肤肥大细胞增多症的一种罕见变体的重要性，这种变体可能会与多发性幼年黄色肉芽肿相混淆。
