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小脑后下动脉梗死与颈部肌张力障碍相关:一例报告

Posterior Inferior Cerebellar Artery Infarct Associated With Cervical Dystonia: A Case Report.

作者信息

Anto Anandu M, Mokan Dasan Saran Lal A, Molina Marcos, Mandalapu Navya, Dhallu Manjeet

机构信息

Internal Medicine, BronxCare Health System, New York City, USA.

Neurology, BronxCare Health System, New York City, USA.

出版信息

Cureus. 2025 Aug 21;17(8):e90682. doi: 10.7759/cureus.90682. eCollection 2025 Aug.

Abstract

Cerebellar infarcts, particularly those involving the posterior inferior cerebellar artery (PICA), can present with diverse and atypical neurological symptoms that complicate timely diagnosis. We present the case of an 84-year-old woman with a history of vascular risk factors who developed sudden-onset dizziness, vomiting, and altered mental status, ultimately found to have a right PICA territory infarct on MRI. Notably, on the second day of admission, she developed transient cervical dystonia (CD) characterized by leftward neck deviation and sternocleidomastoid spasm. This focal motor manifestation, in the absence of classic ataxia or cranial nerve deficits, highlights the rare but significant association between cerebellar stroke and dystonia. Neuroanatomical pathways involving the cerebellum, basal ganglia, and vestibular systems, particularly the Guillain-Mollaret triangle (GMT) and corticocerebellar loops, may underlie such movement disorders. Additionally, ischemia of structures such as the accessory nerve or imbalance in vestibular tone may contribute to cervical posturing. The patient's dystonia improved spontaneously with supportive care and baclofen, supporting the theory of transient post-ischemic hypersensitivity rather than fixed structural damage. This case emphasizes the importance of recognizing central causes of acquired torticollis to avoid misdiagnosis and delays in stroke management, particularly in elderly patients presenting with subtle posterior circulation symptoms.

摘要

小脑梗死,尤其是那些累及小脑后下动脉(PICA)的梗死,可能会出现多样且不典型的神经症状,这使得及时诊断变得复杂。我们报告了一例84岁女性患者,她有血管危险因素病史,突发头晕、呕吐和精神状态改变,最终MRI检查发现为右侧PICA供血区梗死。值得注意的是,在入院第二天,她出现了短暂性颈部肌张力障碍(CD),表现为颈部向左偏斜和胸锁乳突肌痉挛。这种局灶性运动表现,在没有典型共济失调或脑神经缺损的情况下,凸显了小脑卒中和肌张力障碍之间罕见但重要的关联。涉及小脑、基底神经节和前庭系统的神经解剖通路,特别是Guillain - Mollaret三角(GMT)和皮质小脑环路,可能是此类运动障碍的基础。此外,副神经等结构的缺血或前庭张力失衡可能导致颈部姿势异常。患者的肌张力障碍通过支持治疗和巴氯芬自发改善,支持了短暂性缺血后超敏反应而非固定结构性损伤的理论。该病例强调了认识后天性斜颈的中枢性病因以避免误诊和延误卒中治疗的重要性,特别是在表现为细微后循环症状的老年患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff2f/12450058/ba2eab5bb271/cureus-0017-00000090682-i01.jpg

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