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一名54岁男性首次癫痫发作后出现的发作后皮肤瘀点疹(鲑鱼皮样疹)

Postictal Petechial Skin Rash (Trout Skin) After a First Epileptic Seizure in a 54-Year-Old Man.

作者信息

Bopp Annina, Albrecht Sarah, Huber Lars C

机构信息

Clinic of Internal Medicine, City Hospital Zurich Triemli, Zurich, Switzerland.

出版信息

Am J Case Rep. 2025 Sep 23;26:e948740. doi: 10.12659/AJCR.948740.

Abstract

BACKGROUND Postictal petechiae have a recognized but rare association with epileptic seizures, possibly due to increased capillary pressure and blood leakage. The appearance has been likened to that of trout skin, and the pinpoint skin petechiae retain their color even when pressure is applied. This report describes the case of a 54-year-old man with a postictal petechial skin rash (trout skin) following a first epileptic seizure. CASE REPORT A 54-year-old man arrived at our hospital's emergency room after experiencing a loss of consciousness for the first time. Except for slight disorientation, no focal neurological deficits were found. The only notable clinical abnormality was a petechial rash confined to the face, neck, and chest. Laboratory analysis showed no signs of inflammation or coagulation disorder. Further testing, including computed tomography (CT), magnetic resonance imaging (MRI), and electroencephalography (EEG), revealed no abnormalities. Based on the patient's history, postictal state, tongue biting, and the characteristic petechial rash, we diagnosed a first-time epileptic seizure. Antiepileptic therapy with levetiracetam was initiated. CONCLUSIONS This report highlights the known but rare association of postictal petechiae (trout skin) with epileptic seizures, which is a clinical sign that may assist the clinician in identifying a cause of loss of consciousness when the clinical history is unclear.

摘要

背景

发作后瘀点与癫痫发作有关,这一点已得到公认,但较为罕见,可能是由于毛细血管压力增加和血液渗漏所致。其外观类似于鲑鱼皮,即使施加压力,针尖样皮肤瘀点仍保持其颜色。本报告描述了一名54岁男性在首次癫痫发作后出现发作后瘀点性皮疹(鲑鱼皮)的病例。病例报告:一名54岁男性首次出现意识丧失后抵达我院急诊室。除轻度定向障碍外,未发现局灶性神经功能缺损。唯一明显的临床异常是局限于面部、颈部和胸部的瘀点性皮疹。实验室分析未显示炎症或凝血障碍迹象。进一步检查,包括计算机断层扫描(CT)、磁共振成像(MRI)和脑电图(EEG),均未发现异常。根据患者的病史、发作后状态、咬舌情况以及特征性瘀点性皮疹,我们诊断为首次癫痫发作。开始使用左乙拉西坦进行抗癫痫治疗。结论:本报告强调了发作后瘀点(鲑鱼皮)与癫痫发作之间已知但罕见的关联,这是一种临床体征,在临床病史不明确时可能有助于临床医生确定意识丧失的原因。

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