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宫颈环扎术在合并苗勒管异常和宫颈机能不全的妊娠中的应用:一例报告。

Usage of cervical cerclage in pregnancy with Mullerian anomalies and cervical insufficiency: A case report.

作者信息

Maulida Widya, Suryawan Alfonsus Zeus, Setiawan Dani, Rinaldi Andi, Santoso Tiffanie Almas

机构信息

Department of Obstetrics and Gynecology, Universitas Padjadjaran, Bandung, Indonesia.

Department of Obstetrics and Gynecology, Sumedang District Hospital, Indonesia.

出版信息

SAGE Open Med Case Rep. 2025 Sep 20;13:2050313X251377288. doi: 10.1177/2050313X251377288. eCollection 2025.

DOI:10.1177/2050313X251377288
PMID:40984889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12450273/
Abstract

Usage of cervical cerclage in Mullerian anomalies remains unclear due to the few studies and reports conducted on such cases. This case report wishes to highlight the usage of cervical cerclage in Mullerian abnormalities and repeated preterm labour. A 26-year-old G3P2A0 with 13 weeks of pregnancy came with a history of repeated preterm birth, which ended at 23-24 and 28-29 weeks consecutively. Ultrasound examination revealed that she had 14-15 weeks of pregnancy and cervical length 2.2 cm. The patient was diagnosed with cervical insufficiency, and cervical cerclage was performed. The patient then presented at 36th-37th weeks of pregnancy with labour pain and fetal distress, emergency cesarean section was performed. During the operation bicorporeal uterus was found. The fetus was delivered weighing 2.690 g with 1-min APGAR score of 7 and 5 min at 9. We performed ultrasonography and pelvic MRI 2 months after delivery, which identified a U3bC0V0 as in the European Society of Human Reproduction and Embryology classification and a bicornuate uterus (serosal indentation >1 cm) as in the 2021 American Society of Reproductive Medicine classification. Patient presented with two preterm births and fulfilled classic historic features of cervical insufficiency which history-indicated cerclage is mandatory. Uterine anomalies themselves increase the risk of recurrent pregnancy loss, preterm birth, and cervical insufficiency. Only half of a pregnancy with a bicorporeal uterus lasts till term, and half of it ends up as early preterm pregnancy loss. It is important to diagnose or exclude Mullerian abnormalities in cases of repeated preterm labour or second-trimester pregnancy loss. Usage of cerclage has been useful in some cases, including this case; further research should be conducted for stabilizing the guidelines of cerclage in pregnancy with Mullerian abnormalities.

摘要

由于针对此类病例开展的研究和报告较少,宫颈环扎术在苗勒管异常中的应用仍不明确。本病例报告旨在强调宫颈环扎术在苗勒管异常和反复早产中的应用。一名26岁、孕13周的G3P2A0孕妇因有反复早产史前来就诊,其前两胎分别在孕23 - 24周和28 - 29周早产。超声检查显示她实际孕周为14 - 15周,宫颈长度为2.2厘米。该患者被诊断为宫颈机能不全,并接受了宫颈环扎术。患者在孕36 - 37周时出现宫缩疼痛和胎儿窘迫,遂行急诊剖宫产。术中发现双体子宫。娩出胎儿体重2690克,1分钟Apgar评分7分,5分钟Apgar评分9分。产后2个月我们进行了超声检查和盆腔MRI检查,根据欧洲人类生殖与胚胎学会分类确定为U3bC0V0型,根据2021年美国生殖医学学会分类确定为双角子宫(浆膜凹陷>1厘米)。患者有两次早产史,具备宫颈机能不全的典型历史特征,根据病史提示必须进行环扎术。子宫异常本身会增加复发性流产、早产和宫颈机能不全的风险。双体子宫妊娠只有一半能持续至足月,另一半则以早期早产流产告终。在反复早产或孕中期流产的病例中,诊断或排除苗勒管异常很重要。环扎术在某些病例中,包括本病例,已显示出作用;应进一步开展研究以稳定宫颈环扎术在合并苗勒管异常妊娠中的应用指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/bdf094b0bf9a/10.1177_2050313X251377288-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/985ab9ef4ff9/10.1177_2050313X251377288-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/ff6111758fef/10.1177_2050313X251377288-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/2f2977b6734f/10.1177_2050313X251377288-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/bdf094b0bf9a/10.1177_2050313X251377288-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/985ab9ef4ff9/10.1177_2050313X251377288-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/ff6111758fef/10.1177_2050313X251377288-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/2f2977b6734f/10.1177_2050313X251377288-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b1/12450273/bdf094b0bf9a/10.1177_2050313X251377288-fig4.jpg

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本文引用的文献

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